Non‐coding RNAs in diseases with a focus on osteoarthritis

A Pekáčová, J Baloun, X Švec… - Wiley Interdisciplinary …, 2023 - Wiley Online Library
Osteoarthritis (OA) is a frequent musculoskeletal disorder affecting millions of people
worldwide. Despite advances in understanding the pathogenesis of OA, prognostic …

[HTML][HTML] Non-coding RNAs in cartilage development: an updated review

E Razmara, A Bitaraf, H Yousefi, TH Nguyen… - International journal of …, 2019 - mdpi.com
In the development of the skeleton, the long bones are arising from the process of
endochondral ossification (EO) in which cartilage is replaced by bone. This complex process …

MicroRNA‐140 is expressed in differentiated human articular chondrocytes and modulates interleukin‐1 responses

S Miyaki, T Nakasa, S Otsuki, SP Grogan… - Arthritis & …, 2009 - Wiley Online Library
Objective MicroRNA (miRNA) are a class of noncoding small RNAs that act as negative
regulators of gene expression. MiRNA exhibit tissue‐specific expression patterns, and …

[PDF][PDF] Long intergenic noncoding RNAs mediate the human chondrocyte inflammatory response and are differentially expressed in osteoarthritis cartilage

MJ Pearson, AM Philp, JA Heward… - Arthritis & …, 2016 - Wiley Online Library
Objective To identify long noncoding RNAs (lncRNAs), including long intergenic noncoding
RNAs (lincRNAs), antisense RNAs, and pseudogenes, associated with the inflammatory …

microRNAs and cartilage

G Gibson, H Asahara - Journal of Orthopaedic Research, 2013 - Wiley Online Library
ABSTRACT microRNAs are small non‐coding RNAs that in the last decade have emerged
as overarching regulators of gene expression. Their abundance, ability to repress a large …

MicroRNA expression in osteoarthritis: A meta-analysis

H Liu, L Yan, X Li, D Li, G Wang, NN Shen, JJ Li… - Clinical and …, 2023 - Springer
Osteoarthritis (OA) is one of the most prevalent musculoskeletal diseases globally, leading
to chronic disability and poor prognosis. One of the approaches for optimizing OA treatment …

Genome‐wide microRNA screening reveals miR‐582‐5p as a mesenchymal stem cell‐specific microRNA in subchondral bone of the human knee joint

P Wang, R Dong, B Wang, Z Lou, J Ying… - Journal of Cellular …, 2019 - Wiley Online Library
Emerging evidence suggests that microRNAs (miRNAs) may be pathologically involved in
osteoarthritis (OA). Subchondral bone (SCB) sclerosis is accounted for the knee …

Nociceptive related microRNAs and their role in rheumatoid arthritis

S Reyes-Long, JL Cortes-Altamirano… - Molecular Biology …, 2020 - Springer
Rheumatoid Arthritis (RA) is an autoimmune disease with unknown etiology and a global
incidence around 1%, a positive family history increases the risk of RA roughly three to five …

[HTML][HTML] Current status and strategy of microRNA research for cartilage development and osteoarthritis pathogenesis

H Asahara - Journal of bone metabolism, 2016 - synapse.koreamed.org
MicroRNAs (miRNAs), which are small (~ 21 nucleotides) non-coding RNAs, are important
players in endochondral ossification, articular cartilage homeostasis, and arthritis …

[HTML][HTML] Identification of differentially expressed microRNAs in knee anterior cruciate ligament tissues surgically removed from patients with osteoarthritis

B Li, L Bai, P Shen, Y Sun… - … journal of molecular …, 2017 - spandidos-publications.com
The degradation of cruciate ligaments is frequently observed in degenerative joint diseases,
such as osteoarthritis (OA). The present study aimed to identify the differentially expressed …