MicroRNAs, a group of small, noncoding RNAs that post-transcriptionally regulate gene
expression, play important roles in chondrocyte function and in the development of …

Background Osteoarthritis is the most common form of arthritis and a major socioeconomic
burden. Our study is the first to explore the association between serum microRNA levels and …

Non-coding RNAs have distinct regulatory roles in the pathogenesis of joint diseases
including osteoarthritis (OA) and rheumatoid arthritis (RA). As the amount of high-throughput …

Objective Osteoarthritis (OA) is characterized by the chronic and progressive deterioration of
articular cartilage. Chondrocyte senescence could lead to a shift in the balance between …

Objective MicroRNAs act locally and systemically to impact osteoarthritis (OA)
pathophysiology, but comprehensive profiling of the circulating miRNome in early vs late …

Rheumatoid arthritis (RA) is a common autoimmune disease. The hallmarks of RA are
synovial inflammation and hyperplasia, autoantibody production, systemic features, and …

Ageing is a leading risk factor predisposing cartilage to osteoarthritis. However, little
research has been conducted on the effect of ageing on the expression of small non-coding …

Objective This study investigated mice serum and joint microRNA expression profiles in
ageing and osteoarthritis to elucidate the role of microRNAs in the development and …

Osteoarthritis (OA) is characterized by degeneration of articular cartilage, limited
intraarticular inflammation with synovitis, and changes in peri-articular and subchondral …

Cartilage has limited repair and regeneration capacity, thus damage of cartilage often
results in its dysfunction and even chronic diseases like osteoarthritis (OA). Chondrogenesis …