MicroRNAs in cartilage development, homeostasis, and disease

F Mirzamohammadi, G Papaioannou… - Current osteoporosis …, 2014 - Springer
Abstract microRNAs (miRNAs) regulate gene expression mainly at the posttranscriptional
level. Many different miRNAs are expressed in chondrocytes, and each individual miRNA …

[HTML][HTML] Plasma and synovial fluid microRNAs as potential biomarkers of rheumatoid arthritis and osteoarthritis

K Murata, H Yoshitomi, S Tanida, M Ishikawa… - Arthritis research & …, 2010 - Springer
Introduction MicroRNAs (miRNAs), endogenous small noncoding RNAs regulating the
activities of target mRNAs and cellular processes, are present in human plasma in a stable …

MicroRNA profiling in cartilage ageing

P Balaskas, K Goljanek-Whysall… - … journal of genomics, 2017 - Wiley Online Library
Osteoarthritis (OA) is the most common age‐related joint disorder in man. MicroRNAs
(miRNA), a class of small noncoding RNAs, are potential therapeutic targets for regulating …

[HTML][HTML] Expression profile of long noncoding RNAs in cartilage from knee osteoarthritis patients

M Fu, G Huang, Z Zhang, J Liu, Z Huang, B Yu… - Osteoarthritis and …, 2015 - Elsevier
Summary Objectives Long noncoding RNAs (lncRNAs) have emerged as a novel class of
regulatory molecules involved in various biological processes, but their role in osteoarthritis …

The role of microRNAs in cellular senescence and age-related conditions of cartilage and bone: A review

S Weilner, R Grillari-Voglauer, H Redl, J Grillari… - Acta …, 2015 - Taylor & Francis
Background and purpose—We reviewed the current state of research on microRNAs in age-
related diseases in cartilage and bone. Methods—PubMed searches were conducted using …

[HTML][HTML] Long noncoding RNAs: a new regulatory code in osteoarthritis

X Cen, XQ Huang, WT Sun, Q Liu… - American journal of …, 2017 - ncbi.nlm.nih.gov
It is reported that long noncoding RNAs (lncRNAs) were expressed aberrantly in cartilage of
osteoarthritis (OA). Current evidence indicates that lncRNAs not only serve as positive or …

Assessment of the profiling microRNA expression of differentiated and dedifferentiated human adult articular chondrocytes

L Lin, Q Shen, C Zhang, L Chen… - Journal of Orthopaedic …, 2011 - Wiley Online Library
MicroRNA has an important role in regulating gene expression during cell differentiation. In
this study we identified the expression pattern of microRNA in the differentiated and …

Long noncoding RNA related to cartilage injury promotes chondrocyte extracellular matrix degradation in osteoarthritis

Q Liu, X Zhang, L Dai, X Hu, J Zhu, L Li… - Arthritis & …, 2014 - Wiley Online Library
Objective Long noncoding RNAs (lncRNAs) play crucial regulatory roles in diverse biologic
processes, but knowledge of lncRNAs in osteoarthritis (OA) is limited. The aim of this study …

MicroRNAs as new player in rheumatoid arthritis

I Duroux-Richard, J Presumey, G Courties, S Gay… - Joint Bone Spine, 2011 - Elsevier
MicroRNAs (miRNAs) are small noncoding RNA molecules that negatively regulate gene
expression at the post-transcriptional level. Currently, there are 939 mature human miRNA …

The inflammatory circuitry of miR-149 as a pathological mechanism in osteoarthritis

P Santini, L Politi, PD Vedova, R Scandurra… - Rheumatology …, 2014 - Springer
Osteoarthritis (OA) is a multifactorial degenerative pathology, whose progression is
exacerbated by pro-inflammatory cytokines signaling. Among the changes triggered in …