PCA3 long noncoding RNA modulates the expression of key cancer-related genes in LNCaP prostate cancer cells
AEG Lemos, LB Ferreira, NM Batoreu, PP de Freitas… - Tumor Biology, 2016 - Springer
Abstract Prostate cancer antigen 3 (PCA3) is a prostate-specific long noncoding RNA
(lncRNA) involved in the control of prostate cancer (PCa) cell survival, through modulating …
(lncRNA) involved in the control of prostate cancer (PCa) cell survival, through modulating …
[HTML][HTML] PCA3 noncoding RNA is involved in the control of prostate-cancer cell survival and modulates androgen receptor signaling
Background PCA3 is a non-coding RNA (ncRNA) that is highly expressed in prostate cancer
(PCa) cells, but its functional role is unknown. To investigate its putative function in PCa …
(PCa) cells, but its functional role is unknown. To investigate its putative function in PCa …
[HTML][HTML] The long non-coding RNA PCA3: an update of its functions and clinical applications as a biomarker in prostate cancer
AEG Lemos, A da Rocha Matos, LB Ferreira - Oncotarget, 2019 - ncbi.nlm.nih.gov
Abstract Prostate cancer antigen 3 (PCA3) is an overexpressed prostate long non-coding
RNA (lncRNA), transcribed from an intronic region at the long arm of human chromosome …
RNA (lncRNA), transcribed from an intronic region at the long arm of human chromosome …
Transcriptome Sequencing Reveals PCAT5 as a Novel ERG-Regulated Long Noncoding RNA in Prostate Cancer
Castration-resistant prostate cancers (CRPC) that arise after the failure of androgen-
blocking therapies cause most of the deaths from prostate cancer, intensifying the need to …
blocking therapies cause most of the deaths from prostate cancer, intensifying the need to …
A review on the role of PCA3 lncRNA in carcinogenesis with an especial focus on prostate cancer
The prostate cancer antigen 3 (PCA3) is a long non-coding RNA (lncRNA) with high level of
specificity for prostate cancer. This lncRNA has fundamental effects in the prostate …
specificity for prostate cancer. This lncRNA has fundamental effects in the prostate …
[HTML][HTML] Identification of a long non-coding RNA as a novel biomarker and potential therapeutic target for metastatic prostate cancer
F Crea, A Watahiki, L Quagliata, H Xue, L Pikor… - Oncotarget, 2014 - ncbi.nlm.nih.gov
Metastatic prostate cancer (PCa) is still an incurable disease. Long non-coding RNAs
(lncRNAs) may be an overlooked source of cancer biomarkers and therapeutic targets. We …
(lncRNAs) may be an overlooked source of cancer biomarkers and therapeutic targets. We …
[HTML][HTML] A PCA3 gene-based transcriptional amplification system targeting primary prostate cancer
Targeting specifically primary prostate cancer (PCa) cells for immune therapy, gene therapy
or molecular imaging is of high importance. The PCA3 long non-coding RNA is a unique …
or molecular imaging is of high importance. The PCA3 long non-coding RNA is a unique …
[HTML][HTML] The long non-coding RNA PCAT-1 promotes prostate cancer cell proliferation through cMyc
Long non-coding RNAs (lncRNAs) represent an emerging layer of cancer biology,
contributing to tumor proliferation, invasion, and metastasis. Here, we describe a role for the …
contributing to tumor proliferation, invasion, and metastasis. Here, we describe a role for the …
[HTML][HTML] Diagnostic significance of urinary long non-coding PCA3 RNA in prostate cancer
T Wang, X Qu, J Jiang, P Gao, D Zhao, X Lian, X Li - Oncotarget, 2017 - ncbi.nlm.nih.gov
Abstract Prostate cancer antigen 3 (PCA3) is a long non-coding RNA, which was found
increased expression in CaP patients than healthy individual. In this study, the individual …
increased expression in CaP patients than healthy individual. In this study, the individual …
Knockdown of long non-coding RNA prostate cancer-associated ncRNA transcript 1 inhibits multidrug resistance and c-Myc-dependent aggressiveness in colorectal …
L Qiao, X Liu, Y Tang, Z Zhao, J Zhang… - Molecular and cellular …, 2018 - Springer
The long non-coding RNA (lncRNA) prostate cancer-associated ncRNA transcript 1 (PCAT-
1) has been shown to promote prostate cancer cell proliferation through c-Myc and is …
1) has been shown to promote prostate cancer cell proliferation through c-Myc and is …