[HTML][HTML] A comprehensive review of cancer MicroRNA therapeutic delivery strategies
A Forterre, H Komuro, S Aminova, M Harada - Cancers, 2020 - mdpi.com
In the field of molecular oncology, microRNAs (miRNAs) and their role in regulating
physiological processes and cancer pathogenesis have been a revolutionary discovery over …
physiological processes and cancer pathogenesis have been a revolutionary discovery over …
Nanocarriers for microRNA delivery in cancer medicine
I Fernandez-Piñeiro, I Badiola, A Sanchez - Biotechnology advances, 2017 - Elsevier
The number of deaths caused by cancer is expected to increase partly due to the lack of
selectivity and undesirable systemic effects of current treatments. Advances in the …
selectivity and undesirable systemic effects of current treatments. Advances in the …
Non-viral based miR delivery and recent developments
AE Labatut, G Mattheolabakis - European Journal of Pharmaceutics and …, 2018 - Elsevier
Abstract miRNAs are promising therapeutic targets or tools for the treatment of numerous
diseases, with most prominently, cancer. The inherent capacity of these short nucleic acids …
diseases, with most prominently, cancer. The inherent capacity of these short nucleic acids …
In vivo delivery of miRNAs for cancer therapy: challenges and strategies
Abstract MicroRNAs (miRNAs), small non-coding RNAs, can regulate post-transcriptional
gene expressions and silence a broad set of target genes. miRNAs, aberrantly expressed in …
gene expressions and silence a broad set of target genes. miRNAs, aberrantly expressed in …
Recent progress in microRNA delivery for cancer therapy by non-viral synthetic vectors
H Wang, Y Jiang, H Peng, Y Chen, P Zhu… - Advanced drug delivery …, 2015 - Elsevier
MicroRNAs (miRNAs) are small non-coding RNAs that regulate gene expression. Because
of significant changes in their expression in cancer, miRNAs are believed to be key factors in …
of significant changes in their expression in cancer, miRNAs are believed to be key factors in …
Combination of microRNA therapeutics with small-molecule anticancer drugs: mechanism of action and co-delivery nanocarriers
X Dai, C Tan - Advanced drug delivery reviews, 2015 - Elsevier
MicroRNAs (miRNAs) regulate multiple molecular pathways vital for the hallmarks of cancer
with a high degree of biochemical specificity and potency. By restoring tumor suppressive …
with a high degree of biochemical specificity and potency. By restoring tumor suppressive …
Nanoparticle-mediated delivery of therapeutic genes: focus on miRNA therapeutics
M Muthiah, IK Park, CS Cho - Expert opinion on drug delivery, 2013 - Taylor & Francis
Introduction: Micro RNAs (miRNA) are 21–23 nucleotides long and regulate the expression
of coding genes by binding imperfectly with their 3′ UTR region. The miRNA profile is …
of coding genes by binding imperfectly with their 3′ UTR region. The miRNA profile is …
Nanoscale delivery systems for microRNAs in cancer therapy
S Boca, D Gulei, AA Zimta, A Onaciu, L Magdo… - Cellular and Molecular …, 2020 - Springer
Concomitant with advances in research regarding the role of miRNAs in sustaining
carcinogenesis, major concerns about their delivery options for anticancer therapies have …
carcinogenesis, major concerns about their delivery options for anticancer therapies have …
[HTML][HTML] MicroRNA therapeutics in cancer: current advances and challenges
Simple Summary Cancer is a complex disease associated with deregulation of numerous
genes. In addition, redundant cellular pathways limit efficiency of monotarget drugs in …
genes. In addition, redundant cellular pathways limit efficiency of monotarget drugs in …
[HTML][HTML] miRacle of microRNA-driven cancer nanotherapeutics
Simple Summary The discovery of microRNAs has revolutionized the world of science and
opened up new opportunities in cancer treatment. miRNA dysregulation plays a crucial role …
opened up new opportunities in cancer treatment. miRNA dysregulation plays a crucial role …