[HTML][HTML] A comprehensive review of cancer MicroRNA therapeutic delivery strategies

A Forterre, H Komuro, S Aminova, M Harada - Cancers, 2020 - mdpi.com
In the field of molecular oncology, microRNAs (miRNAs) and their role in regulating
physiological processes and cancer pathogenesis have been a revolutionary discovery over …

Nanocarriers for microRNA delivery in cancer medicine

I Fernandez-Piñeiro, I Badiola, A Sanchez - Biotechnology advances, 2017 - Elsevier
The number of deaths caused by cancer is expected to increase partly due to the lack of
selectivity and undesirable systemic effects of current treatments. Advances in the …

Non-viral based miR delivery and recent developments

AE Labatut, G Mattheolabakis - European Journal of Pharmaceutics and …, 2018 - Elsevier
Abstract miRNAs are promising therapeutic targets or tools for the treatment of numerous
diseases, with most prominently, cancer. The inherent capacity of these short nucleic acids …

In vivo delivery of miRNAs for cancer therapy: challenges and strategies

Y Chen, DY Gao, L Huang - Advanced drug delivery reviews, 2015 - Elsevier
Abstract MicroRNAs (miRNAs), small non-coding RNAs, can regulate post-transcriptional
gene expressions and silence a broad set of target genes. miRNAs, aberrantly expressed in …

Recent progress in microRNA delivery for cancer therapy by non-viral synthetic vectors

H Wang, Y Jiang, H Peng, Y Chen, P Zhu… - Advanced drug delivery …, 2015 - Elsevier
MicroRNAs (miRNAs) are small non-coding RNAs that regulate gene expression. Because
of significant changes in their expression in cancer, miRNAs are believed to be key factors in …

Combination of microRNA therapeutics with small-molecule anticancer drugs: mechanism of action and co-delivery nanocarriers

X Dai, C Tan - Advanced drug delivery reviews, 2015 - Elsevier
MicroRNAs (miRNAs) regulate multiple molecular pathways vital for the hallmarks of cancer
with a high degree of biochemical specificity and potency. By restoring tumor suppressive …

Nanoparticle-mediated delivery of therapeutic genes: focus on miRNA therapeutics

M Muthiah, IK Park, CS Cho - Expert opinion on drug delivery, 2013 - Taylor & Francis
Introduction: Micro RNAs (miRNA) are 21–23 nucleotides long and regulate the expression
of coding genes by binding imperfectly with their 3′ UTR region. The miRNA profile is …

Nanoscale delivery systems for microRNAs in cancer therapy

S Boca, D Gulei, AA Zimta, A Onaciu, L Magdo… - Cellular and Molecular …, 2020 - Springer
Concomitant with advances in research regarding the role of miRNAs in sustaining
carcinogenesis, major concerns about their delivery options for anticancer therapies have …

[HTML][HTML] MicroRNA therapeutics in cancer: current advances and challenges

S Reda El Sayed, J Cristante, L Guyon, J Denis… - Cancers, 2021 - mdpi.com
Simple Summary Cancer is a complex disease associated with deregulation of numerous
genes. In addition, redundant cellular pathways limit efficiency of monotarget drugs in …

[HTML][HTML] miRacle of microRNA-driven cancer nanotherapeutics

G Kara, B Arun, GA Calin, B Ozpolat - Cancers, 2022 - mdpi.com
Simple Summary The discovery of microRNAs has revolutionized the world of science and
opened up new opportunities in cancer treatment. miRNA dysregulation plays a crucial role …