Identification of Key Genes and Regulatory Pathways in Multiple Sclerosis Brain Samples: A Meta-Analysis of Micro-Array Datasets
MI Jansen, A Castorina - International Journal of Molecular Sciences, 2023 - mdpi.com
Multiple sclerosis (MS) is an autoimmune disorder of the central nervous system (CNS)
whose aetiology is only partly understood. Investigating the intricate transcriptional changes …
whose aetiology is only partly understood. Investigating the intricate transcriptional changes …
Gene expression profiling in multiple sclerosis brain
R Dutta, BD Trapp - Neurobiology of disease, 2012 - Elsevier
Multiple sclerosis (MS) is a chronic inflammatory demyelinating disease of the central
nervous system and the leading cause of non-traumatic neurological disability in young …
nervous system and the leading cause of non-traumatic neurological disability in young …
Identification of key target genes and biological pathways in multiple sclerosis brains using microarray data obtained from the Gene Expression Omnibus database
W Zheng, Y Chen, H Chen, W Xiao, YJ Liang… - Neurological …, 2018 - Taylor & Francis
Objective: The purpose of this study was to investigate critical genes in multiple sclerosis
(MS) using microarray data from brain tissue in MS. Materials: The expression profile data …
(MS) using microarray data from brain tissue in MS. Materials: The expression profile data …
Transcriptomic meta-analysis of multiple sclerosis and its experimental models
BBR Raddatz, F Hansmann, I Spitzbarth, A Kalkuhl… - PloS one, 2014 - journals.plos.org
Background Multiple microarray analyses of multiple sclerosis (MS) and its experimental
models have been published in the last years. Objective Meta-analyses integrate the …
models have been published in the last years. Objective Meta-analyses integrate the …
Investigation of differentially expressed genes and dysregulated pathways involved in multiple sclerosis
Multiple Sclerosis (MS) is a neurodegenerative autoimmune and organ-specific
demyelinating disorder, known to affect the central nervous system (CNS). While genetic …
demyelinating disorder, known to affect the central nervous system (CNS). While genetic …
Gene expression changes underlying cortical pathology: clues to understanding neurological disability in multiple sclerosis
R Dutta - Multiple Sclerosis Journal, 2013 - journals.sagepub.com
Multiple sclerosis (MS) is a chronic inflammatory demyelinating disease of the central
nervous system with an unknown etiology. The clinical disease course is variable, with the …
nervous system with an unknown etiology. The clinical disease course is variable, with the …
Network-based analysis of differentially expressed genes in cerebrospinal fluid (CSF) and blood reveals new candidate genes for multiple sclerosis
Background The involvement of multiple genes and missing heritability, which are dominant
in complex diseases such as multiple sclerosis (MS), entail using network biology to better …
in complex diseases such as multiple sclerosis (MS), entail using network biology to better …
Genomics in multiple sclerosis—current state and future directions
M Comabella, R Martin - Journal of neuroimmunology, 2007 - Elsevier
Microarray-based gene expression profiling of large numbers of genes or even the whole
genome has only recently become possible. Several studies have employed this technology …
genome has only recently become possible. Several studies have employed this technology …
Microarray gene expression profiling analysis combined with bioinformatics in multiple sclerosis
M Liu, X Hou, P Zhang, Y Hao, Y Yang, X Wu… - Molecular biology …, 2013 - Springer
Multiple sclerosis (MS) is the most prevalent demyelinating disease and the principal cause
of neurological disability in young adults. Recent microarray gene expression profiling …
of neurological disability in young adults. Recent microarray gene expression profiling …
A comprehensive exploration of the transcriptomic landscape in multiple sclerosis: a systematic review
L Chiricosta, S Blando, S D'Angiolini… - International Journal of …, 2023 - mdpi.com
Multiple Sclerosis (MS) is, to date, an incurable disease of the nervous system characterized
by demyelination. Several genetic mutations are associated with the disease but they are …
by demyelination. Several genetic mutations are associated with the disease but they are …