Surface PEGylation of Mesoporous Silica Nanorods (MSNR): Effect on loading, release, and delivery of mitoxantrone in hypoxic cancer cells

A Wani, GHL Savithra, A Abyad, S Kanvinde, J Li… - Scientific reports, 2017 - nature.com
Mesoporous silica nanomaterials show great potential to deliver chemotherapeutics for
cancer treatment. The key challenges in the development of injectable mesoporous silica …

Sterically stabilised polymeric mesoporous silica nanoparticles improve doxorubicin efficiency: Tailored cancer therapy

T Moodley, M Singh - Molecules, 2020 - mdpi.com
The fruition, commercialisation and clinical application combining nano-engineering,
nanomedicine and material science for utilisation in drug delivery is becoming a reality. The …

Mannosylated poly (acrylic acid)-coated mesoporous silica nanoparticles for anticancer therapy

H Lee, M Choi, HE Kim, M Jin, WJ Jeon, M Jung… - Journal of Controlled …, 2022 - Elsevier
Although mesoporous silica nanoparticles (MSNs) are widely used as anticancer drug
carriers, unmodified MSNs induce off-target effects and at high doses, there are adverse …

Mesoporous silica nanoparticles for targeted and stimuli‐responsive delivery of chemotherapeutics: A review

A Rahikkala, SAP Pereira, P Figueiredo… - Advanced …, 2018 - Wiley Online Library
Mesoporous silica nanoparticles (MSNs) exhibit the typical characteristics of inorganic
materials that make them promising drug delivery carriers for cancer therapy. Their structural …

Recent advances in mesoporous silica nanoparticles for targeted drug delivery applications

AM Abu-Dief, M Alsehli, A Al-Enizi… - Current Drug …, 2022 - ingentaconnect.com
Nanotechnology provides the means to design and fabricate delivery vehicles capable of
overcoming physiologically imposed obstacles and undesirable side effects of systemic drug …

Doxorubicin hydrochloride-loaded mesoporous silica nanoparticles inhibit non-small cell lung cancer metastasis by suppressing VEGF-mediated angiogenesis

M Zhang, L Jiang - Journal of biomedical nanotechnology, 2016 - ingentaconnect.com
Mesoporous silica nanoparticles (MSNs) are widely used nanoparticles with a pore rich
structure that is suitable for drug delivery. Here, we used MSNs to carry and deliver …

Mesoporous silica nanoparticles as drug delivery vehicles in cancer

A Watermann, J Brieger - Nanomaterials, 2017 - mdpi.com
Even though cancer treatment has improved over the recent decades, still more specific and
effective treatment concepts are mandatory. Surgical removal is not always possible …

Biocompatibility, biodistribution, and drug‐delivery efficiency of mesoporous silica nanoparticles for cancer therapy in animals

J Lu, M Liong, Z Li, JI Zink, F Tamanoi - Small, 2010 - Wiley Online Library
Mesoporous silica nanoparticles (MSNs) are a promising material for drug delivery. In this
Full Paper, MSNs are first shown to be well tolerated, as demonstrated by serological …

Mesoporous silica nanoparticles: synthesis, classification, drug loading, pharmacokinetics, biocompatibility, and application in drug delivery

Z Li, Y Zhang, N Feng - Expert opinion on drug delivery, 2019 - Taylor & Francis
ABSTRACT Introduction: Mesoporous silica nanoparticles (MSNs) feature a high surface
area and large pore volume, uniform and tunable pore size, and stable framework; thus, they …

Application of mesoporous silica nanoparticles as drug delivery carriers for chemotherapeutic agents

Y Alyassin, EG Sayed, P Mehta, K Ruparelia… - Drug Discovery …, 2020 - Elsevier
Highlights•Structural and geometrical features of mesoporous silica can benefit drug
delivery.•Coupled with therapeutic agents, targeting for a host of cancers is …