Protection against Alzheimer's disease by luteolin: Role of brain glucose regulation, anti‐inflammatory activity, and the gut microbiota‐liver‐brain axis
JW Daily, S Kang, S Park - Biofactors, 2021 - Wiley Online Library
Luteolin is a widely distributed flavone herbs and vegetables. It has anti‐oxidant and anti‐
inflammatory activities and improves glucose metabolism by potentiating insulin sensitivity …
inflammatory activities and improves glucose metabolism by potentiating insulin sensitivity …
Bioavailability and pharmaco-therapeutic potential of luteolin in overcoming Alzheimer's disease
F Ali, YH Siddique - … (Formerly Current Drug Targets-CNS & …, 2019 - ingentaconnect.com
Luteolin is a naturally occurring, yellow crystalline flavonoid found in numerous dietary
supplements we frequently have in our meals. Studies in the last 2 decades have revealed …
supplements we frequently have in our meals. Studies in the last 2 decades have revealed …
The combination of luteolin and l-theanine improved Alzheimer disease–like symptoms by potentiating hippocampal insulin signaling and decreasing …
Luteolin and l-theanine have anti-inflammatory, antioxidant, and possible antidiabetic
activities, and they may synergistically protect against dementia. Here, we hypothesized that …
activities, and they may synergistically protect against dementia. Here, we hypothesized that …
Luteolin as a potential preventive and therapeutic candidate for Alzheimer's disease
Y Kwon - Experimental Gerontology, 2017 - Elsevier
Amyloid cascade hypothesis is the main theoretical framework describing the development
of Alzheimer's disease (AD). However, most clinical trials of therapy targeting amyloid-β …
of Alzheimer's disease (AD). However, most clinical trials of therapy targeting amyloid-β …
Luteolin as an anti-inflammatory and neuroprotective agent: A brief review
Abstract According to the World Health Organization, two billion people will be aged 60
years or older by 2050. Aging is a major risk factor for a number of neurodegenerative …
years or older by 2050. Aging is a major risk factor for a number of neurodegenerative …
[HTML][HTML] Luteolin inhibits microglia and alters hippocampal-dependent spatial working memory in aged mice
S Jang, RN Dilger, RW Johnson - The Journal of nutrition, 2010 - Elsevier
A dysregulated overexpression of inflammatory mediators by microglia may facilitate
cognitive aging and neurodegeneration. Considerable evidence suggests the flavonoid …
cognitive aging and neurodegeneration. Considerable evidence suggests the flavonoid …
Luteolin protects against high fat diet-induced cognitive deficits in obesity mice
Y Liu, X Fu, N Lan, S Li, J Zhang, S Wang, C Li… - Behavioural brain …, 2014 - Elsevier
The epidemic and experimental studies have confirmed that the obesity can lead to
neuroinflammation, neurodegenerative diseases and adversely affect cognition. Despite the …
neuroinflammation, neurodegenerative diseases and adversely affect cognition. Despite the …
Deciphering the Potential Neuroprotective Effects of Luteolin against Aβ1–42-Induced Alzheimer's Disease
The current study was undertaken to unveil the protective effects of Luteolin, a natural
flavonoid, against amyloid-beta (Aβ1–42)-induced neuroinflammation, amyloidogenesis …
flavonoid, against amyloid-beta (Aβ1–42)-induced neuroinflammation, amyloidogenesis …
Luteolin attenuates diabetes-associated cognitive decline in rats
Diabetes mellitus can cause dysfunction of the central nervous system called “diabetic
encephalopathy”. Although various oral drugs are used to treat diabetes, they do not prevent …
encephalopathy”. Although various oral drugs are used to treat diabetes, they do not prevent …
[HTML][HTML] Protective effects of luteolin against amyloid beta-induced oxidative stress and mitochondrial impairments through peroxisome proliferator-activated receptor γ …
Z He, X Li, Z Wang, Y Cao, S Han, N Li, J Cai, S Cheng… - Redox Biology, 2023 - Elsevier
Alzheimer's disease (AD) is a devastating neurodegenerative disorder characterized by the
deposition of β-amyloid (Aβ) peptides and dysfunction of mitochondrion, which result in …
deposition of β-amyloid (Aβ) peptides and dysfunction of mitochondrion, which result in …
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