In the last few years, the number of bacteria with enhanced resistance to conventional
antibiotics has dramatically increased. Most of such bacteria belong to regular microbial …

Pathogens resistant to most conventional anti-infectives are a harbinger of the need to
discover and develop novel anti-infective agents and strategies. Endogenous host defense …

The increasing prevalence of multidrug-resistant bacterial infections necessitates the
exploration of novel paradigms for anti-infective therapy. Antimicrobial peptides (AMPs), also …

Antimicrobial host defense peptides (HDPs) are a critical component of the innate immunity
with microbicidal, endotoxin-neutralizing, and immunostimulatory properties. HDPs kill …

New infection treatments are urgently needed to combat the rising threat of multi-drug
resistant bacteria. Despite early clinical set-backs attention has re-focused on host defense …

Infectious diseases caused by bacteria, viruses or fungi are among the leading causes of
death worldwide. The emergence of drug-resistance mechanisms, especially among …

The golden era of antibiotics, heralded by the discovery of penicillin, has long been
challenged by the emergence of antimicrobial resistance (AMR). Host defense peptides …

Host defence peptides (HDPs) are multi-functional inducers and effectors of host immunity.
Through their direct antimicrobial activity HDPs have for been successfully utilized for many …

Host defence peptides (HDPs) are short cationic molecules produced by the immune
systems of most multicellular organisms and play a central role as effector molecules of …

Host defense peptides (HDPs) are relatively small, mostly cationic, amphipathic, and of
variable length, sequence, and structure. The majority of these peptides exhibit broad …