[HTML][HTML] Single-Nucleotide Polymorphisms in LPA Explain Most of the Ancestry-Specific Variation in Lp(a) Levels in African Americans

RC Deo, JG Wilson, C Xing, K Lawson, WHL Kao… - PloS one, 2011 - journals.plos.org
Lipoprotein (a)(Lp (a)) is an important causal cardiovascular risk factor, with serum Lp (a)
levels predicting atherosclerotic heart disease and genetic determinants of Lp (a) levels …

Genetic variants in the apolipoprotein (a) gene and coronary heart disease

Y Li, MM Luke, D Shiffman, JJ Devlin - Circulation: Cardiovascular …, 2011 - Am Heart Assoc
Two independent single-nucleotide polymorphisms (SNPs) in the gene encoding
apolipoprotein (a)(LPA) have been shown to be associated with coronary heart disease …

Lipoprotein (a) and diabetes mellitus

C Lamina, NC Ward - Atherosclerosis, 2022 - Elsevier
Lp (a) and diabetes are both known and established risk factors for the development of
cardiovascular disease. However, studies trying to link both risk factors find an inverse …

Frequent LPA KIV-2 Variants Lower Lipoprotein(a) Concentrations and Protect Against Coronary Artery Disease

JF Schachtl-Riess, A Kheirkhah, R Grüneis… - Journal of the American …, 2021 - jacc.org
Abstract Background Lipoprotein (a)(Lp (a)) concentrations are a major independent risk
factor for coronary artery disease (CAD) and are mainly determined by variation in LPA. Up …

Lipoprotein (a) concentrations, isoform size, and risk of type 2 diabetes: a Mendelian randomisation study

PR Kamstrup, BG Nordestgaard - The lancet Diabetes & …, 2013 - thelancet.com
Background Low concentrations of lipoprotein (a) in plasma are associated with increased
risk of type 2 diabetes, but whether this association is causal is unclear. Variations in the …