[HTML][HTML] Thymoquinone restores liver fibrosis and improves oxidative stress status in a lipopolysaccharide-induced inflammation model in rats

F Asgharzadeh, R Bargi, F Beheshti… - Avicenna journal of …, 2017 - ncbi.nlm.nih.gov
Objective: Liver fibrosis is the primary sign of chronic liver injury induced by various causes.
Thymoquinone (TQ) is the major ingredient of Nigella sativa with several beneficial effects …

Thymoquinone alleviates thioacetamide-induced hepatic fibrosis and inflammation by activating LKB1–AMPK signaling pathway in mice

T Bai, Y Yang, YL Wu, S Jiang, JJ Lee, LH Lian… - International …, 2014 - Elsevier
The current study was conducted to investigate the anti-fibrotic effect and its possible
underlying mechanisms of thymoquinone (TQ) against hepatic fibrosis in vivo. TQ is the …

Thymoquinone, the most prominent constituent of Nigella sativa, attenuates liver damage in streptozotocin-induced diabetic rats via regulation of oxidative stress …

SA Almatroodi, AM Alnuqaydan, MA Alsahli, AA Khan… - Applied Sciences, 2021 - mdpi.com
Diabetes mellitus (DM) is a multifaceted metabolic disorder that results in dysfunction and
failure of various organs. The present study aimed to evaluate the role of Thymoquinone …

[HTML][HTML] Thymoquinone prevents myocardial and perivascular fibrosis induced by chronic lipopolysaccharide exposure in male rats:-thymoquinone and cardiac …

F Asgharzadeh, R Bargi, F Beheshti… - Journal of …, 2018 - ncbi.nlm.nih.gov
Objectives Thymoquinone (TQ) is one of the active ingredients of herbal plants such as
Nigella sativa L.(NS) which has beneficial effects on the body. The beneficial effects of TQ …

[HTML][HTML] Thymoquinone protects the rat kidneys against renal fibrosis

R Bargi, F Asgharzadeh, F Beheshti… - Research in …, 2017 - journals.lww.com
Thymoquinone (TQ) is the main active ingredient of Nigella sativa seeds with various
pharmacological effects. The aim of this study was to investigate the effect of TQ on renal …

[PDF][PDF] Thymoquinone supplementation ameliorates acute endotoxemia-induced liver dysfunction in rats.

GK Helal - Pakistan journal of pharmaceutical sciences, 2010 - academia.edu
Endotoxemia caused by lipopolysaccharide (LPS) produced an inflammatory condition
contributing to multiple organ failure. This study was carried out to investigate the effects of …

[PDF][PDF] Hepatoprotective activity of a phytotherapeutic formula on thioacetamide-induced liver fibrosis model

MK Kantah, R Kobayashi, J Sollano, Y Naito… - Acta Biomed, 2011 - iris.unict.it
Hepatic fibrosis is a widespread alteration in the liver that primarily consists of increased
collagen deposition in the tissue. The aim of the present study was to evaluate the protective …

Therapeutic effects of thymoquinone in doxorubicin‐induced hepatotoxicity via oxidative stress, inflammation and apoptosis

AT Akin, E Öztürk, E Kaymak… - Anatomia, histologia …, 2021 - Wiley Online Library
Cancer is a lethal disease that is characterized by uncontrolled cell division and
proliferation, and it results in death in many organisms. Doxorubicin (DOX) is a therapeutic …

Yohimbine ameliorates liver inflammation and fibrosis by regulating oxidative stress and Wnt/β-catenin pathway

N Sharma, R Sistla, SB Andugulapati - Phytomedicine, 2024 - Elsevier
Background and purpose Chronic liver injury, caused by various aetiologies, causes
recurrent tissue damage, culminating in decreased liver regenerative ability and resulting in …

[HTML][HTML] The protective effect of Nigella sativa against liver injury: a review

H Mollazadeh, H Hosseinzadeh - Iranian journal of basic medical …, 2014 - ncbi.nlm.nih.gov
Abstract Nigella sativa (Family Ranunculaceae) is a widely used medicinal plant throughout
the world. N. sativa is referred in the Middle East as a part of an overall holistic approach to …