[HTML][HTML] Effect of RGD coupled MDA-7/IL-24 on apoptosis induction in a hepatocellular carcinoma cell line

E Hosseini, SY Hosseini… - Molecular …, 2017 - spandidos-publications.com
The melanoma differentiation-associated gene‑7 (MDA-7) gene, also termed interleukin‑24
(IL‑24), is a tumor suppressor gene that induces apoptosis in a broad scope of malignant …

[HTML][HTML] Effects of melanoma differentiation associated gene-7 (MDA-7/IL-24) on apoptosis of liver cancer cells via regulating the expression of B-cell lymphoma-2

Q Mo, L Liu, G Bao, T Li - Oncology Letters, 2019 - spandidos-publications.com
The present study investigated the mechanism of selective killing of liver cancer cells of
melanoma differentiation associated gene-7 (MDA-7, also called IL-24α) in order to provide …

Enhanced Apoptosis-Inducing Function of MDA-7/IL-24 RGD Mutant Via the Increased Adhesion to Tumor Cells

DS Pei, ZX Yang, BF Zhang, XX Yin, LT Li… - Journal of Interferon & …, 2012 - liebertpub.com
Melanoma differentiation-associated gene-7 (mda-7)/interleukin-24 (IL-24) has shown
potent tumor cell apoptosis inducing capacity in multiple cancers. However, the apoptosis …

Oncolytic adenovirus-mediated MDA-7/IL-24 overexpression enhances antitumor activity in hepatocellular carcinoma cell lines.

CW Xiao, XB Xue, H Zhang, W Gao, Y Yu… - Hepatobiliary & …, 2010 - europepmc.org
Background Melanoma differentiation-associated gene-7 (MDA-7)/interleukin-24 (IL-24) is a
novel tumor suppressor gene, which has suppressor activity in a broad spectrum of human …

[HTML][HTML] MDA-7/IL-24 suppresses human ovarian carcinoma growth in vitro and in vivo

B Gopalan, M Shanker, S Chada, R Ramesh - Molecular cancer, 2007 - Springer
Background Previous studies showed that the human melanoma differentiation-associated
gene-7 (mda-7), also known as interleukin-24 (IL-24), has potent antitumor activity against …

Antitumor effect and underlying mechanism of RGD-modified adenovirus mediated IL-24 expression on myeloid leukemia cells

X Yu, W Xia, S Li, J Blumenfeld, B Zhang, J Yang… - International …, 2015 - Elsevier
Abstract Interleukin-24 (IL-24), a member of the IL-10 cytokine gene family, causes growth
suppression and apoptosis in various solid tumor cells. However, the effects of IL-24 on …

[HTML][HTML] MDA-7/IL-24 suppresses tumor adhesion and invasive potential in hepatocellular carcinoma cell lines

W Huo, ZM Li, XM Zhu, YM Bao… - Oncology …, 2013 - spandidos-publications.com
Melanoma differentiation associated gene-7 (MDA-7)/interleukin‑24 (IL-24) has been
considered as a tumor-suppressor gene, which suppresses the growth and induces the …

Melanoma differentiation associated gene-7/interleukin-24 promotes tumor cell-specific apoptosis through both secretory and nonsecretory pathways

M Sauane, IV Lebedeva, Z Su, H Choo, A Randolph… - Cancer research, 2004 - AACR
Melanoma differentiation associated gene-7/interleukin-24 (Mda-7/IL-24), a novel member
of the IL-10 family of cytokines, uniquely displays cancer-specific apoptosis-inducing activity …

[HTML][HTML] Impact of RGD peptide tethering to IL24/mda-7 (Melanoma Differentiation Associated Gene-7) on apoptosis induction in hepatocellular carcinoma cells

S Bina, F Shenavar, M Khodadad… - Asian Pacific Journal …, 2015 - koreascience.kr
Background: Melanoma differentiation-associated gene-7 (MDA-7)/interleukin-24 (IL-24), a
unique tumor suppressor gene, has killing activity in a broad spectrum of cancer cells …

Cytokine and tumor cell apoptosis inducing activity of mda-7/IL-24

RV Gopalkrishnan, M Sauane, PB Fisher - International …, 2004 - Elsevier
Melanoma Differentiation Associated gene-7 (mda-7)/IL-24 has shown potent tumor cell
apoptosis inducing capacity in multiple cancers, making it a strong candidate for use as a …