Inappropriate dosing of direct oral anticoagulants in patients with atrial fibrillation

A Sugrue, D Sanborn, M Amin, M Farwati… - The American journal of …, 2021 - Elsevier
Direct Oral Anticoagulants (DOACs) require dose adjustment based on specific patient
characteristics, making them prone to incorrect dosing. The current study aimed to evaluate …

The comparison of inappropriate-low-doses use among 4 direct oral anticoagulants in patients with atrial fibrillation: from the database of a single-center registry

T Sato, Y Aizawa, K Fuse, S Fujita, Y Ikeda… - Journal of Stroke and …, 2018 - Elsevier
Background Inappropriate doses of direct oral anticoagulants (DOACs) are often prescribed.
This study evaluated the prevalence, outcomes, and predictors of the prescription of …

[HTML][HTML] Inappropriate dosing of direct oral anticoagulants in patients with atrial fibrillation

K Lavoie, MH Turgeon, C Brais… - Journal of Atrial …, 2016 - ncbi.nlm.nih.gov
Atrial fibrillation (AF) is a common cardiovascular disease for which newer oral
anticoagulants are available. The main objective of this study was to evaluate the …

[HTML][HTML] Characteristics and outcomes in patients with atrial fibrillation receiving direct oral anticoagulants in off-label doses

A Briasoulis, Y Gao, C Inampudi, P Alvarez… - BMC cardiovascular …, 2020 - Springer
Background We evaluated adherence to dosing criteria for patients with atrial fibrillation (AF)
taking dabigatran or rivaroxaban and the impact of off-label dosing on thromboembolic and …

Mortality in patients with atrial fibrillation receiving nonrecommended doses of direct oral anticoagulants

AJ Camm, F Cools, S Virdone, JP Bassand… - Journal of the American …, 2020 - jacc.org
Background The recommended doses for direct oral anticoagulants (DOACs) to prevent
stroke and systemic embolism (SE) in patients with atrial fibrillation (AF) are described in …

Effect of non‐recommended doses versus recommended doses of direct oral anticoagulants in atrial fibrillation patients: A meta‐analysis

X Liu, M Huang, C Ye, X Xiao, C Yan - Clinical Cardiology, 2021 - Wiley Online Library
Background Several observational studies have shown that the inappropriate dosing use of
direct oral anticoagulants (DOACs) in atrial fibrillation (AF) that does not conform to …

Meta-analysis comparing inappropriately low dose versus standard dose of direct oral anticoagulants in patients with atrial fibrillation

K Kido, M Shimizu, T Shiga, M Hashiguchi - Journal of the American …, 2022 - Elsevier
Background The appropriateness of direct oral anticoagulant (DOAC) dosing has been the
issue in the real-world setting, and inappropriately lower DOAC dose may not be as effective …

Suboptimal use of oral anticoagulants in atrial fibrillation: has the introduction of direct oral anticoagulants improved prescribing practices?

EA Alamneh, L Chalmers, LR Bereznicki - American journal of …, 2016 - Springer
Abstract Background and Objectives Atrial fibrillation (AF) and the associated risk of stroke
are emerging epidemics throughout the world. Suboptimal use of oral anticoagulants for …

[HTML][HTML] Inappropriate direct oral anticoagulant dosing in atrial fibrillation patients is associated with prescriptions for outpatients rather than inpatients: a single-center …

M Miyazaki, K Matsuo, M Uchiyama… - … Health Care and …, 2020 - Springer
Background Inappropriate dosing of direct oral anticoagulants (DOACs) has been
associated with clinical safety and efficacy; however, little is known about clinical data …

Inappropriate doses of direct oral anticoagulants in real-world clinical practice: prevalence and associated factors. A subanalysis of the FANTASIIA Registry

M Ruiz Ortiz, J Muñiz, P Raña Míguez, I Roldán… - Ep …, 2018 - academic.oup.com
Aims To describe the prevalence and associated factors of inappropriate doses of direct oral
anticoagulants (DOAC) in a national registry of patients of real clinical practice. Methods and …