Pathways for horizontal gene transfer in bacteria revealed by a global map of their plasmids

S Redondo-Salvo, R Fernández-López, R Ruiz… - Nature …, 2020 - nature.com
Plasmids can mediate horizontal gene transfer of antibiotic resistance, virulence genes, and
other adaptive factors across bacterial populations. Here, we analyze genomic composition …

Mechanisms of, and barriers to, horizontal gene transfer between bacteria

CM Thomas, KM Nielsen - Nature reviews microbiology, 2005 - nature.com
Mutation and horizontal gene transfer (HGT) continually give rise to new bacterial
genotypes. Infrequently, such new bacterial genotypes establish and spread in the larger …

Beyond horizontal gene transfer: the role of plasmids in bacterial evolution

J Rodríguez-Beltrán, J DelaFuente… - Nature Reviews …, 2021 - nature.com
Plasmids have a key role in bacterial ecology and evolution because they mobilize
accessory genes by horizontal gene transfer. However, recent studies have revealed that …

Large-scale network analysis captures biological features of bacterial plasmids

M Acman, L van Dorp, JM Santini, F Balloux - Nature communications, 2020 - nature.com
Many bacteria can exchange genetic material through horizontal gene transfer (HGT)
mediated by plasmids and plasmid-borne transposable elements. Here, we study the …

COPLA, a taxonomic c lassifier of pla smids

S Redondo-Salvo, R Bartomeus-Peñalver, L Vielva… - BMC …, 2021 - Springer
Background Plasmids are mobile genetic elements, key in the dissemination of antibiotic
resistance, virulence determinants and other adaptive traits in bacteria. Obtaining a robust …

[图书][B] Horizontal gene pool: bacterial plasmids and gene spread

CM Thomas - 2000 - books.google.com
Bacteria are the most ubiquitous of all organisms. Responsible for a number of diseases and
for many of the chemical cycles on which life depends, they are genetically adaptable. Vital …

Reconciling the many faces of lateral gene transfer

JG Lawrence, H Ochman - TRENDS in Microbiology, 2002 - cell.com
The various methods for detecting potential lateral gene transfer events typically uncover
different sets of genes. Because the procedures used to recognize transferred genes ask …

Tradeoff between horizontal and vertical modes of transmission in bacterial plasmids

PE Turner, VS Cooper, RE Lenski - Evolution, 1998 - Wiley Online Library
It has been hypothesized that there is a fundamental conflict between horizontal (infectious)
and vertical (intergenerational) modes of parasite transmission. Activities of a parasite that …

Horizontal gene transfer and the origin of species: lessons from bacteria

F De la Cruz, J Davies - Trends in microbiology, 2000 - cell.com
In bacteria, horizontal gene transfer (HGT) is widely recognized as the mechanism
responsible for the widespread distribution of antibiotic resistance genes, gene clusters …

Predicting plasmid promiscuity based on genomic signature

H Suzuki, H Yano, CJ Brown, EM Top - Journal of bacteriology, 2010 - Am Soc Microbiol
Despite the important contribution of self-transmissible plasmids to bacterial evolution, little
is understood about the range of hosts in which these plasmids have evolved. Our goal was …