A 3D poly (ethylene glycol)-based tumor angiogenesis model to study the influence of vascular cells on lung tumor cell behavior
Tumor angiogenesis is critical to tumor growth and metastasis, yet much is unknown about
the role vascular cells play in the tumor microenvironment. In vitro models that mimic in vivo …
the role vascular cells play in the tumor microenvironment. In vitro models that mimic in vivo …
Mimicking brain tumor-vasculature microanatomical architecture via co-culture of brain tumor and endothelial cells in 3D hydrogels
Glioblastoma (GBM) is an aggressive malignant brain tumor with median survival of 12
months and 5-year survival rate less than 5%. GBM is highly vascularized, and the …
months and 5-year survival rate less than 5%. GBM is highly vascularized, and the …
In Vitro Angiogenesis Induced by Tumor-Endothelial Cell Co-Culture in Bilayered, Collagen I Hydrogel Bioengineered Tumors
CS Szot, CF Buchanan, JW Freeman… - … Engineering Part C …, 2013 - liebertpub.com
Although successful remission has been achieved when cancer is diagnosed and treated
during its earliest stages of development, a tumor that has established neovascularization …
during its earliest stages of development, a tumor that has established neovascularization …
Hydrogels to model 3D in vitro microenvironment of tumor vascularization
A growing number of failing clinical trials for cancer therapy are substantiating the need to
upgrade the current practice in culturing tumor cells and modeling tumor angiogenesis in …
upgrade the current practice in culturing tumor cells and modeling tumor angiogenesis in …
Physical supports from liver cancer cells are essential for differentiation and remodeling of endothelial cells in a HepG2-HUVEC co-culture model
Blood vessel remodeling is crucial in tumor growth. Growth factors released by tumor cells
and endothelium-extracellular matrix interactions are highlighted in tumor angiogenesis …
and endothelium-extracellular matrix interactions are highlighted in tumor angiogenesis …
[HTML][HTML] Development of a 3D angiogenesis model to study tumour–endothelial cell interactions and the effects of anti-angiogenic drugs
A Amann, M Zwierzina, S Koeck, G Gamerith… - Scientific reports, 2017 - nature.com
The tumour microenvironment and tumour angiogenesis play a critical role in the
development and therapy of many cancers, but in vitro models reflecting these …
development and therapy of many cancers, but in vitro models reflecting these …
Oxygen-controlled three-dimensional cultures to analyze tumor angiogenesis
Tumor angiogenesis is controlled by the integrated action of physicochemical and biological
cues; however, the individual contributions of these cues are not well understood. We have …
cues; however, the individual contributions of these cues are not well understood. We have …
The influence of hyaluronic acid and glioblastoma cell coculture on the formation of endothelial cell networks in gelatin hydrogels
Glioblastoma (GBM) is the most common and deadly form of brain cancer. Interactions
between GBM cells and vasculature in vivo contribute to poor clinical outcomes, with GBM …
between GBM cells and vasculature in vivo contribute to poor clinical outcomes, with GBM …
Vascularized lung cancer model for evaluating the promoted transport of anticancer drugs and immune cells in an engineered tumor microenvironment
D Kim, KS Hwang, EU Seo, S Seo… - Advanced …, 2022 - Wiley Online Library
The tumor microenvironment (TME) is the environment around the tumor, including blood
vessels, immune cells, fibroblasts, signaling molecules, and the extracellular matrix (ECM) …
vessels, immune cells, fibroblasts, signaling molecules, and the extracellular matrix (ECM) …
In vitro modeling of solid tumor interactions with perfused blood vessels
Molecular crosstalk between intra-tumor blood vessels and tumor cells plays many critical
roles in tumorigenesis and cancer metastasis. However, it has been very difficult to …
roles in tumorigenesis and cancer metastasis. However, it has been very difficult to …