Effects on cell viability

M Guzman - Cannabinoids, 2005 - Springer
Cannabinoids are known to control the cell survival/death decision, leading to different
outcomes that depend on the nature of the target cell and its proliferative or differentiation …

Cannabinoids and cell fate

M Guzmán, C Sánchez, I Galve-Roperh - Pharmacology & therapeutics, 2002 - Elsevier
Cannabinoids recently have been shown to control the cell survival/death decision. Thus,
cannabinoids induce growth arrest or apoptosis in a number of transformed neural and non …

Control of the cell survival/death decision by cannabinoids

M Guzmán, C Sánchez, I Galve-Roperh - Journal of molecular medicine, 2001 - Springer
Cannabinoids, the active components of Cannabis sativa (marijuana), and their derivatives
produce a wide spectrum of central and peripheral effects, some of which may have clinical …

Cannabinoids as modulators of cell death: clinical applications and future directions

BM Fonseca, NA Teixeira… - Reviews of Physiology …, 2017 - Springer
Endocannabinoids are bioactive lipids that modulate various physiological processes
through G-protein-coupled receptors (CB1 and CB2) and other putative targets. By sharing …

High concentrations of cannabinoids activate apoptosis in human U373MG glioma cells

M Widmer, CO Hanemann… - Journal of neuroscience …, 2008 - Wiley Online Library
Cannabinoids bind to two G‐protein‐coupled receptors, CB1 and CB2, expressed by
neurons and cells of the immune system, respectively. Glioma cells (astrocyte‐derived brain …

Involvement of cannabinoids in cellular proliferation

ML López-Rodríguez, A Viso… - Mini reviews in …, 2005 - ingentaconnect.com
The endogenous canabinoid system (ECS) is involved in the regulation of an important
number of central and peripheral physiological effects. Among all these functions, the control …

Antitumorigenic effects of cannabinoids beyond apoptosis

N Freimuth, R Ramer, B Hinz - Journal of Pharmacology and Experimental …, 2010 - ASPET
According to the World Health Organization, the cases of death caused by cancer will have
been doubled until the year 2030. By 2010, cancer is expected to be the number one cause …

Cannabinoid signaling in glioma cells

A Ellert-Miklaszewska, IA Ciechomska, B Kaminska - Glioma Signaling, 2020 - Springer
Cannabinoids are a group of structurally heterogeneous but pharmacologically related
compounds, including plant-derived cannabinoids, synthetic substances and endogenous …

Hypothesis: cannabinoid therapy for the treatment of gliomas?

G Velasco, I Galve-Roperh, C Sánchez, C Blázquez… - …, 2004 - Elsevier
Gliomas, in particular glioblastoma multiforme or grade IV astrocytoma, are the most
frequent class of malignant primary brain tumours and one of the most aggressive forms of …

Cannabinoids–a new weapon against cancer?

M Pokrywka, J Góralska, B Solnica - Advances in Hygiene and …, 2016 - phmd.pl
Cannabis has been cultivated by man since Neolithic times. It was used, among others for
fiber and rope production, recreational purposes and as an excellent therapeutic agent. The …