Accelerated lung function decline has been associated with increased risk of cardiovascular
disease (CVD) in a general population, but little is known about this association in chronic …

Background Estimates for lung function decline in chronic obstructive pulmonary disease
(COPD) have differed by study setting and have not been described in a UK primary care …

Purpose Chronic obstructive pulmonary disease (COPD) is one of the leading causes of
death worldwide. Impaired lung function is associated with heightened risk for death …

Background: Rapid forced expiratory volume in 1 s (FEV1) decliners have been considered
a unique subgroup of patients with chronic obstructive pulmonary disease (COPD). Rapid …

Rationale: Chronic obstructive pulmonary disease (COPD) can develop not only through a
lung function trajectory dominated by an accelerated decline of FEV1 from normal maximally …

Background Chronic obstructive pulmonary disease (COPD) is thought to result from an
accelerated decline in forced expiratory volume in 1 second (FEV1) over time. Yet it is …

Background Early diagnosis of COPD is often not achieved due to limited recognition and
limited access to the pulmonary function test. Our hypothesis was that lung function decline …

Objective Spirometric lung function is usually used to evaluate respiratory health. However,
the impact of lung function on extra-pulmonary diseases and all-cause mortality has not …

Background: Early identification of patients with COPD and prone to more rapid decline in
lung function is of particular interest from both a prognostic and therapeutic point of view …

Lung function level and decline are each predictive of morbidity and mortality. Evaluation of
the combined effect of these measurements may help further identify high-risk groups. Using …