Microfluidic analysis of red blood cell deformability
Q Guo, SP Duffy, K Matthews, AT Santoso… - Journal of …, 2014 - Elsevier
A common indicator of rheological dysfunction is a measurable decrease in the deformability
of red blood cells (RBCs). Decreased RBC deformability is associated with cellular stress or …
of red blood cells (RBCs). Decreased RBC deformability is associated with cellular stress or …
Biomechanical properties of red blood cells in health and disease towards microfluidics
G Tomaiuolo - Biomicrofluidics, 2014 - pubs.aip.org
Red blood cells (RBCs) possess a unique capacity for undergoing cellular deformation to
navigate across various human microcirculation vessels, enabling them to pass through …
navigate across various human microcirculation vessels, enabling them to pass through …
Advances in the measurement of red blood cell deformability: A brief review
J Kim, HY Lee, S Shin - Journal of Cellular Biotechnology, 2015 - content.iospress.com
Red blood cells (RBCs) exhibit a unique deformability, which enables them to change shape
reversibly in response to an external force. The deformability of RBCs allows them to flow in …
reversibly in response to an external force. The deformability of RBCs allows them to flow in …
Alterations in red blood cell deformability during storage: a microfluidic approach
JCA Cluitmans, V Chokkalingam… - BioMed Research …, 2014 - Wiley Online Library
Red blood cells (RBCs) undergo extensive deformation when travelling through the
microcapillaries. Deformability, the combined result of properties of the membrane …
microcapillaries. Deformability, the combined result of properties of the membrane …
Mechanical signature of red blood cells flowing out of a microfluidic constriction is impacted by membrane elasticity, cell surface-to-volume ratio and diseases
Despite the fact that Red Blood Cells (RBCs) have been intensively studied in the past 50
years to characterize mechanical phenotypes associated with both healthy and pathological …
years to characterize mechanical phenotypes associated with both healthy and pathological …
Theoretical model and experimental study of red blood cell (RBC) deformation in microchannels
N Korin, A Bransky, U Dinnar - Journal of biomechanics, 2007 - Elsevier
The motion and deformation of red blood cells (RBCs) flowing in a microchannel were
studied using a theoretical model and a novel automated rheoscope. The theoretical model …
studied using a theoretical model and a novel automated rheoscope. The theoretical model …
Technologies for measuring red blood cell deformability
K Matthews, ES Lamoureux, ME Myrand-Lapierre… - Lab on a Chip, 2022 - pubs.rsc.org
Human red blood cells (RBCs) are approximately 8 μm in diameter, but must repeatedly
deform through capillaries as small as 2 μm in order to deliver oxygen to all parts of the …
deform through capillaries as small as 2 μm in order to deliver oxygen to all parts of the …
Mechanical response of red blood cells entering a constriction
NF Zeng, WD Ristenpart - Biomicrofluidics, 2014 - pubs.aip.org
Most work on the dynamic response of red blood cells (RBCs) to hydrodynamic stress has
focused on linear velocity profiles. Relatively little experimental work has examined how …
focused on linear velocity profiles. Relatively little experimental work has examined how …
Microfluidic deformability analysis of the red cell storage lesion
K Matthews, ME Myrand-Lapierre, RR Ang… - Journal of …, 2015 - Elsevier
A key challenge in transfusion medicine research and clinical hematology is to develop a
simple and non-destructive method to measure the quality of each blood unit prior to use …
simple and non-destructive method to measure the quality of each blood unit prior to use …
A system for the high-throughput measurement of the shear modulus distribution of human red blood cells
Reduced deformability of red blood cells (RBCs) can affect the hemodynamics of the
microcirculation and reduce oxygen transport efficiency. It is also well known that reduced …
microcirculation and reduce oxygen transport efficiency. It is also well known that reduced …
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