Adenosine receptors represent a family of G‐protein coupled receptors that are ubiquitously
expressed in a wide variety of tissues. This family contains four receptor subtypes: A1 and …

Responses to adenosine are governed by selective activation of distinct G proteins by
adenosine receptor (AR) subtypes. The A 2a AR couples via G s to adenylyl cyclase …

Adenosine receptors (ARs) are members of the G protein-coupled receptor family and
mediate the multiple physiological effects of adenosine. Currently, four AR subtypes have …

Four adenosine receptors have been cloned from many mammalian and some non-
mammalian species. In each case the translated part of the receptor is encoded by two …

Adenosine produces a wide variety of effects throughout the body via activation of cell
surface adenosine receptors. Adenosine receptors belong to the family of seven …

The A 2a adenosine receptor is a member of the G-protein coupled receptor family, and its
activation stimulates cyclic AMP production. To determine the residues which are involved in …

Endogenous adenosine is a widely distributed upstream regulator of a broad spectrum of
neurotransmitters, receptors, and signaling pathways that converge to contribute to the …

The A1 adenosine receptor is the best characterized of the widely distributed purinergic
receptor family. The purified brain A1 receptor is a monomeric 35‐to 36‐kDa glycoprotein …

Through this presentation, I have attempted to highlight some of the work that has been
carried out in my laboratory over the past four years. We have strived to take a systemic …

Our knowledge of A1 and A2ARs has grown dramatically since they were first defined by
Burnstock. With the recent purification of the A1AR and the cDNA cloning of the A2AR, an …