Gold nanoparticles (AuNPs) are relevant in nanomedicine for drug delivery in the vascular
system, where endothelial cells are the first point of contact. We investigated the uptake of …

A new in vitro model system, adding advection and shear stress associated with a flowing
medium, is proposed for the investigation of nanoparticles uptake and toxicity towards …

Gold nanoparticles (AuNPs) have potential biomedical and scientific applications. In this
study, we evaluated the uptake and internalization of FBS‐coated 20 nm AuNPs into lung …

More information characterizing the biological responses to nanoparticles is needed to allow
the US Food and Drug Administration to evaluate the safety and effectiveness of products …

The selective entry of nanoparticles into target tissues is the key factor which determines
their tissue distribution. Entry is primarily controlled by microvascular endothelial cells, which …

Background The use of gold nanoparticles (AuNPs) for diagnostic applications and for drug
and gene-delivery is currently under intensive investigation. For such applications …

Gold nanoparticles (AuNPs) are currently used in several fields including biomedical
applications, although no conclusive information on their cytotoxicity is available. For this …

Gold nanoparticles (AuNPs) of ultrafine size have drawn attention for their use in drug
delivery systems. Tissue toxicity may be an issue when AuNPs are used for such …

In this study, the in vitro uptake by fibroblasts and in vivo biodistribution of 15 nm 11-
mercaptoundecanoicacid-protected gold nanoparticles (AuNPs-MUA) and 3 nm glutathione …

Nanoscience/technology is a burgeoning field with tremendous potential for biomedical
applications. For nanomedicinal applications of engineered nanomaterials, it is extremely …