Previous work showed that administration of antigen-expressing apoptotic cells in vivo
results in antigen-specific CD8+ T-cell responses independent of Toll-like receptor …

Natural killer (NK) cells recognize tumor cells and virus-infected cells and attack without
being sensitized to antigens. The development of the antitumor/antivirus activities of NK cells …

After recognition, NK cells can kill susceptible target cells through perforin-dependent
mechanisms or by inducing death receptor-mediated apoptosis, and they can also secrete …

Natural killer cells were named after their ability to mediate spontaneous cytotoxicity during
innate immune responses. However, it has become clear in recent years that they play an …

Natural Killer (NK) cells are classically considered innate immune effector cells involved in
the first line of defense against infected and malignant cells. More recently, NK cells have …

Recent cancer treatment modalities have been intensively focused on immunotherapy. The
success of chimeric antigen receptor T cell therapy for treatment of refractory B cell acute …

Natural killer (NK) cells fulfill essential accessory functions for the priming of antigen-specific
cytotoxic T lymphocytes (CTLs). On the basis of a NKG2D-ligand–positive tumor model, we …

Natural killer (NK) cells were viewed traditionally as cytotoxic effector cells whose rapid
killing of infected and transformed cells without preactivation provides a first line of defense …

Increased evidence of cross-talk between NK cells and other immune cells has enhanced
the possibilities of exploiting the interplay between the activation and inhibition of NK cells …

NK cells are the major lymphocyte subset of the innate immune system that mediates
antiviral and anti-tumor responses. It is well established that they develop mechanisms to …