Background: The incidence of gallstones in the Tibetan population is increasing rapidly.
Previous studies indicated that genetic variation located in the cholesterol metabolism …

Background Gallstone disease is one of the most common digestive disorders, affecting
more than 30 million Americans. Previous twin studies suggest a heritability of 25% for …

Abstract Background and Aims Gallstone disease (GD) is a common disease of multigenetic
origin; however, the major susceptibility loci for GD in human populations remain …

Aim Gallstones have a prevalence of 20-40% in European populations and cause significant
morbidity. Gallstones form from cholesterol and calcium bilirubinate and knowledge of …

Gallstones Disease (GSD) is one of the most common digestive diseases requiring
hospitalization and surgical procedures in the world. GSD has a high prevalence in …

Background & Aims A genome-wide association study (GWAS) of 280 cases identified the
hepatic cholesterol transporter ABCG8 as a locus associated with risk for gallstone disease …

Cholesterol gallstone disease, one of the commonest digestive diseases in western
countries, is induced by an imbalance in cholesterol metabolism, which involves intestinal …

Objective To investigate the risk factors for gallstones in Tibetan Plateau. Methods A total of
254 patients who underwent ultrasound examination in a fasting state in Shigatse People's …

Objective Cholesterol gallstone disease (CGD) is a multifactorial and multistep disease.
Apart from female gender and increasing age being the documented non-modifiable risk …

Methods A genome wide scan was performed in twelve families with gallstone disease
using fluorescence-labeled microsatellite markers. Genehunter and Batchlink of Linkage …