[HTML][HTML] LncRNA-BLACAT1 facilitates proliferation, migration and aerobic glycolysis of pancreatic cancer cells by repressing CDKN1C via EZH2-induced H3K27me3

X Zhou, W Gao, H Hua, Z Ji - Frontiers in Oncology, 2020 - frontiersin.org
Objective To investigate the role of lncRNA-BLACAT1 in promoting H3K27 trimethylation of
CDKN1C gene by recruiting EZH2 to regulate CCNE on glycolysis and mitochondrial …

Long non-coding RNA LINC01133 silencing exerts antioncogenic effect in pancreatic cancer through the methylation of DKK1 promoter and the activation of Wnt …

YC Weng, J Ma, J Zhang, JC Wang - Cancer biology & therapy, 2019 - Taylor & Francis
Recent studies have acknowledged the critical roles played by long non-coding RNAs
(lncRNAs) in the development and progression of pancreatic cancer. Therefore, the present …

Epigenetic silencing of LncRNA LINC00261 promotes c-myc-mediated aerobic glycolysis by regulating miR-222-3p/HIPK2/ERK axis and sequestering IGF2BP1

S Zhai, Z Xu, J Xie, J Zhang, X Wang, C Peng, H Li… - Oncogene, 2021 - nature.com
Long noncoding RNAs have been identified as key regulators in the progression of various
cancers. LINC00261 has been reported as a tumor suppressor in multiple cancers …

A reciprocal feedback between N6-methyladenosine reader YTHDF3 and lncRNA DICER1-AS1 promotes glycolysis of pancreatic cancer through inhibiting maturation …

Y Hu, J Tang, F Xu, J Chen, Z Zeng, S Han… - Journal of Experimental …, 2022 - Springer
Background Glycolysis is a pivotal process in metabolic reprogramming of tumorigenesis.
Previous research has indicated that lncRNAs might play crucial roles in glycolysis of …

ALKBH5-mediated m6A demethylation of KCNK15-AS1 inhibits pancreatic cancer progression via regulating KCNK15 and PTEN/AKT signaling

Y He, HQ Yue, Y Cheng, Z Ding, Z Xu, C Lv… - Cell death & …, 2021 - nature.com
Long noncoding RNAs (lncRNAs) are regarded as crucial regulators in tumor progression.
Potassium two pore domain channel subfamily K member 15 and WISP2 antisense RNA 1 …

LncRNA CDKN2B-AS1 promotes cell viability, migration, and invasion of hepatocellular carcinoma via sponging miR-424-5p

X Shen, Y Li, F He, J Kong - Cancer Management and Research, 2020 - Taylor & Francis
Objective Hepatocellular carcinoma (HCC) results in high mortality and metastasis. In this
study, the effects of long non-coding RNA (lncRNA) CDKN2B-AS1 on the progression of …

Long non‑coding RNA BCYRN1 promotes glycolysis and tumor progression by regulating the miR‑149/PKM2 axis in non‑small‑cell lung cancer

N Lang, C Wang, J Zhao, F Shi… - Molecular Medicine …, 2020 - spandidos-publications.com
Cancer cells use aerobic glycolysis to sustain their proliferation. Long non‑coding RNA brain
cytoplasmic RNA 1 (BCYRN1) has been reported to act as an oncogene in non‑small‑cell …

[HTML][HTML] Methylation-mediated LINC00261 suppresses pancreatic cancer progression by epigenetically inhibiting c-Myc transcription

S Liu, Y Zheng, Y Zhang, J Zhang, F Xie, S Guo… - Theranostics, 2020 - ncbi.nlm.nih.gov
Background: Due to the limitations of strategies for its early diagnosis and treatment,
pancreatic cancer (PC) remains a substantial human health threat. We previously …

[HTML][HTML] LncRNA KTN1-AS1 promotes tumor growth of hepatocellular carcinoma by targeting miR-23c/ERBB2IP axis

L Zhang, L Wang, Y Wang, T Chen, R Liu… - Biomedicine & …, 2019 - Elsevier
Long non-coding RNAs (lncRNAs) are critical regulators in the tumorigenesis and
metastasis of hepatocellular carcinoma (HCC). LncRNA KTN1 antisense RNA 1 (KTN1-AS1) …

Yin Yang 1-induced LINC00667 up-regulates pyruvate dehydrogenase kinase 1 to promote proliferation, migration and invasion of cholangiocarcinoma cells by …

J Li, C Guan, Z Hu, L Liu, Z Su, P Kang, X Jiang, Y Cui - Human Cell, 2021 - Springer
Cholangiocarcinoma (CCA) is one of the most aggressive and lethal malignancies. Long
noncoding RNAs (lncRNAs) are being found to play crucial roles in CCA progression. This …