Adenosine A2A-dopamine D2 receptor–receptor heteromers. Targets for neuro-psychiatric disorders
Emerging evidence shows that G protein-coupled receptors can form homo-and heteromers.
These include adenosine A2A receptor–dopamine D2 receptor heteromers, which are most …
These include adenosine A2A receptor–dopamine D2 receptor heteromers, which are most …
Dopamine D1 and adenosine A1 receptors form functionally interacting heteromeric complexes
S Ginés, J Hillion, M Torvinen… - Proceedings of the …, 2000 - National Acad Sciences
The possible molecular basis for the previously described antagonistic interactions between
adenosine A1 receptors (A1R) and dopamine D1 receptors (D1R) in the brain have been …
adenosine A1 receptors (A1R) and dopamine D1 receptors (D1R) in the brain have been …
Adenosine A2A receptor and dopamine D3 receptor interactions: evidence of functional A2A/D3 heteromeric complexes
M Torvinen, D Marcellino, M Canals, LF Agnati… - Molecular …, 2005 - ASPET
Adenosine A2A and dopamine D2 receptors have been shown previously to form
heteromeric complexes and interact at the level of agonist binding, G protein coupling, and …
heteromeric complexes and interact at the level of agonist binding, G protein coupling, and …
Adenosine A2A and dopamine D2 heteromeric receptor complexes and their function
The existence of A 2A-D 2 heteromeric complexes is based on coimmunoprecipitation
studies and on fluorescence resonance energy transfer and bioluminescence resonance …
studies and on fluorescence resonance energy transfer and bioluminescence resonance …
Adenosine A2A Receptor-Antagonist/Dopamine D2 Receptor-Agonist Bivalent Ligands as Pharmacological Tools to Detect A2A-D2 Receptor Heteromers
A Soriano, R Ventura, A Molero, R Hoen… - Journal of medicinal …, 2009 - ACS Publications
Adenosine A2A (A2AR) and dopamine D2 (D2R) receptors mediate the antagonism
between adenosinergic and dopaminergic transmission in striatopallidal GABAergic …
between adenosinergic and dopaminergic transmission in striatopallidal GABAergic …
An update on adenosine A2A-dopamine D2 receptor interactions: implications for the function of G protein-coupled receptors
Adenosine A2A-dopamine D2 receptor interactions play a very important role in striatal
function. A2A-D2 receptor interactions provide an example of the capabilities of information …
function. A2A-D2 receptor interactions provide an example of the capabilities of information …
The importance of the adenosine A2A receptor-dopamine D2 receptor interaction in drug addiction
M Filip, M Zaniewska, M Frankowska… - Current medicinal …, 2012 - ingentaconnect.com
Drug addiction is a serious brain disorder with somatic, psychological, psychiatric, socio-
economic and legal implications in the developed world. Illegal (eg, psychostimulants …
economic and legal implications in the developed world. Illegal (eg, psychostimulants …
Allosteric interactions between agonists and antagonists within the adenosine A2A receptor-dopamine D2 receptor heterotetramer
J Bonaventura, G Navarro… - Proceedings of the …, 2015 - National Acad Sciences
Adenosine A2A receptor (A2AR)-dopamine D2 receptor (D2R) heteromers are key
modulators of striatal neuronal function. It has been suggested that the psychostimulant …
modulators of striatal neuronal function. It has been suggested that the psychostimulant …
Evidence for the heterotetrameric structure of the adenosine A2A–dopamine D2 receptor complex
V Casadó-Anguera, J Bonaventura… - Biochemical Society …, 2016 - portlandpress.com
Heteromers of G-protein-coupled receptors (GPCRs) have emerged as potential novel
targets for drug development. Accumulating evidence indicates that GPCRs can form …
targets for drug development. Accumulating evidence indicates that GPCRs can form …
Biochemical identification of the dopamine D2 receptor domains interacting with the adenosine A2A receptor
M Torvinen, LB Kozell, KA Neve, LF Agnati… - Journal of Molecular …, 2004 - Springer
Functional interactions between adenosine A 2A and dopamine D 2 receptors have been
demonstrated both at the D 2 agonist-binding and second messenger levels. The present …
demonstrated both at the D 2 agonist-binding and second messenger levels. The present …
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