This study was designed to explore the improvement of chitosan oligosaccharides (COS) on
constipation through regulation of gut microbiota. Here, we proved that COS treatment …

Chitosan oligosaccharides (COS) show the potential to support the intestinal health, but the
mechanism and role of COS-derived intestinal microbiota are unknown. We explored the …

This study aimed to optimize the structure and efficacy of xylooligosaccharides (XOSs) from
corn cobs in constipated mice. Structural analysis revealed that XOSs from corn cobs were …

Chitosan oligosaccharides (COS) have shown positive effects on host gut health and
influence on intestinal microbial community. However, the bioactivity and mechanism of …

Constipation is one of the most common gastrointestinal (GI) disorders worldwide. The use
of probiotics to improve constipation is well known. In this study, the effect on loperamide …

Lactulose is a common laxative and has been widely applied to clinical treatment for
constipation. This study aimed to explore the improving effect of lactulose on constipation …

Constipation is one of the most prevalent gastrointestinal tract diseases. Konjac
glucomannan (KGM) dietotherapy can effectively relieve the clinical symptoms of patients …

In this study, the two enzymatic low molecular weight chitosan oligosaccharides (LMW-
COSs), LMW-COS-H and LMW-COS-L, were prepared with average MWs of 879.6 Da and …

The aim of this study is to investigate the effect of chitosan oligosaccharides (COS) on type 2
diabetes mellitus. Wild type C57BL/6J mice or diabetic db/db mice were treated with vehicle …

Chitosan oligosaccharides (COS) have been shown to have potential protective effects
against colitis, but the mechanism underlying this effect has not been fully elucidated. In this …