[HTML][HTML] Nano-formulated siRNA-based therapeutic approaches for cancer therapy

D Jain, SK Prajapati, A Jain, R Singhal - Nano Trends, 2023 - Elsevier
RNAi is a remarkable treatment strategy to knock down gene overexpression in a variety of
disorders, including cancers. RNAi processes allow siRNAs to detect and degrade a …

Nano-scale delivery systems for siRNA delivery in cancer therapy: New era of gene therapy empowered by nanotechnology

N Ebrahimi, MS Manavi, A Nazari, A Momayezi… - Environmental …, 2023 - Elsevier
RNA interference (RNAi) is a unique treatment approach used to decrease a disease's
excessive gene expression, including cancer. SiRNAs may find and destroy homologous …

Advances in siRNA delivery approaches in cancer therapy: challenges and opportunities

H Isazadeh, F Oruji, S Shabani, J Behroozi… - Molecular Biology …, 2023 - Springer
Advancements in the clinical applications of small interfering RNA (siRNA) in cancer therapy
have opened up new possibilities for precision medicine. siRNAs, as powerful genetic tools …

Recent advancements in the design of nanodelivery systems of siRNA for cancer therapy

DN Yadav, MS Ali, AM Thanekar, SV Pogu… - Molecular …, 2022 - ACS Publications
RNA interference (RNAi) has increased the possibility of restoring RNA drug targets for
cancer treatment. Small interfering RNA (siRNA) is a promising therapeutic RNAi tool that …

A review of the current status of siRNA nanomedicines in the treatment of cancer

P Resnier, T Montier, V Mathieu, JP Benoit, C Passirani - Biomaterials, 2013 - Elsevier
RNA interference currently offers new opportunities for gene therapy by the specific
extinction of targeted gene (s) in cancer diseases. However, the main challenge for nucleic …

Nanoparticle‐mediated siRNA delivery systems for cancer therapy

H Gao, R Cheng, H A. Santos - View, 2021 - Wiley Online Library
The small interfering RNA (siRNA)‐based therapeutics have raised great attention since the
first RNA interference (RNAi)‐derived drug, patisiran, was approved by the US Food and …

Tumor‐targeting multifunctional nanoparticles for siRNA delivery: Recent advances in cancer therapy

SH Ku, K Kim, K Choi, SH Kim… - Advanced healthcare …, 2014 - Wiley Online Library
RNA interference (RNAi) is a naturally occurring regulatory process that controls
posttranscriptional gene expression. Small interfering RNA (siRNA), a common form of RNAi …

Nanoparticle‐mediated siRNA delivery and multifunctional modification strategies for effective cancer therapy

M Chen, C Dong, S Shi - Advanced Materials Technologies, 2021 - Wiley Online Library
RNA interference (RNAi), which can inhibit the expression or transcription of specific genes,
is considered to be a revolutionary tool for mediating gene therapy. Small interfering RNA …

Nanoengineered strategies for siRNA delivery: from target assessment to cancer therapeutic efficacy

DK Mishra, N Balekar, PK Mishra - Drug delivery and translational …, 2017 - Springer
The promise of RNA interference (RNAi) technology in cancer therapeutics aims to deliver
small interfering RNA (siRNA) for silencing of gene expression in cell type-specific pathway …

Precision arrows: Navigating breast cancer with nanotechnology siRNA

N Jayaswal, S Srivastava, S Kumar, SB Sridhar… - International Journal of …, 2024 - Elsevier
Nanotechnology-based drug delivery systems, including siRNA, present an innovative
approach to treating breast cancer, which disproportionately affects women. These systems …