[HTML][HTML] Thymoquinone protects the rat kidneys against renal fibrosis

R Bargi, F Asgharzadeh, F Beheshti… - Research in …, 2017 - journals.lww.com
Thymoquinone (TQ) is the main active ingredient of Nigella sativa seeds with various
pharmacological effects. The aim of this study was to investigate the effect of TQ on renal …

The protective effect of thymoquinone, an anti-oxidant and anti-inflammatory agent, against renal injury: a review

A Ragheb, A Attia, WS Eldin, F Elbarbry… - Saudi Journal of …, 2009 - journals.lww.com
Abstract Thymoquinone (TQ), 2-Isopropyl-5-methyl-1, 4-benzoquinone, is one of the most
active ingredients of Nigella Sativa seeds. TQ has a variety of beneficial properties including …

An overview on renoprotective effects of thymoquinone

H Shaterzadeh-Yazdi, MF Noorbakhsh… - Kidney …, 2018 - karger.com
Background: Kidneys as vital organs remove waste material from blood. Additionally, they
may also have a role in the electrolyte balance, regulation of blood pressure, and red blood …

Thymoquinone improves the kidney and liver changes induced by chronic cyclosporine A treatment and acute renal ischaemia/reperfusion in rats

MM Farag, GO Ahmed, RR Shehata… - Journal of Pharmacy …, 2015 - academic.oup.com
Objectives This study was designed to evaluate the effects of chronic cyclosporine A (CsA)
treatment and acute renal ischaemia/reperfusion (I/R) on the kidney and liver in …

[HTML][HTML] Thymoquinone restores liver fibrosis and improves oxidative stress status in a lipopolysaccharide-induced inflammation model in rats

F Asgharzadeh, R Bargi, F Beheshti… - Avicenna journal of …, 2017 - ncbi.nlm.nih.gov
Objective: Liver fibrosis is the primary sign of chronic liver injury induced by various causes.
Thymoquinone (TQ) is the major ingredient of Nigella sativa with several beneficial effects …

Thymoquinone ameliorates acute renal failure in gentamicin-treated adult male rats

S Samarghandian, M Azimi-Nezhad, H Mehrad-Majd… - Pharmacology, 2015 - karger.com
Background: Gentamicin (GEN) is considered as a main aminoglycoside antibiotic medicine.
The top therapeutic side effect of GEN is nephrotoxicity. The current research was proposed …

[PDF][PDF] Protective effect of Nigella sativa L. extracts and thymoquinone, its active constituent, on renal ischemia-reperfusion-induced oxidative damage in rats

H Hosseinzadeh, R Montahaei - Pharmacologyonline, 2007 - researchgate.net
Generation of reactive oxygen species and lipid peroxidation are associated with tissue
injury following Ischemia/Reperfusion (I/R). Therefore, this model was used to assess the …

[HTML][HTML] The effect of thymoquinone on the renal functions following ischemia-reperfusion injury in the rat

FT Hammad, L Lubbad - International journal of physiology …, 2016 - ncbi.nlm.nih.gov
Introduction: The aim of this study was to investigate the effect of thymoquinone, an
antioxidant phytochemical compound found in the plant Nigella sativa, on the alterations in …

Thymoquinone alleviates doxorubicin induced acute kidney injury by decreasing endoplasmic reticulum stress, inflammation and apoptosis

E Kaymak, E Öztürk, AT Akİn, D Karabulut… - Biotechnic & …, 2022 - Taylor & Francis
Doxorubicin (DOX) is used as an anticancer drug despite its many side effects.
Thymoquinone (THQ) is a plant-derived substance that exhibits antioxidant and anti …

[HTML][HTML] Thymoquinone prevents myocardial and perivascular fibrosis induced by chronic lipopolysaccharide exposure in male rats:-thymoquinone and cardiac …

F Asgharzadeh, R Bargi, F Beheshti… - Journal of …, 2018 - ncbi.nlm.nih.gov
Objectives Thymoquinone (TQ) is one of the active ingredients of herbal plants such as
Nigella sativa L.(NS) which has beneficial effects on the body. The beneficial effects of TQ …