Cryptococcus neoformans is an opportunistic fungal pathogen that threatens individuals with
impaired cell-mediated immunity (CMI). Presently, there are no standardized vaccines …

Cryptococcus neoformans is an opportunistic fungal pathogen that causes life-threatening
pneumonia and meningoencephalitis in immune compromised individuals. Previous studies …

Cryptococcosis is a fungal disease caused by multiple Cryptococcus serotypes; particularly
C. neoformans (serotypes A and D) and C. gattii (serotypes B and C). To date, there is no …

Many aspects of the host response to invasive cryptococcal infections remain poorly
understood. In order to explore the pathobiology of infection with common clinical strains, we …

Cryptococcus neoformans and C. gattii, the etiologic agents of cryptococcosis, cause over
100,000 deaths worldwide every year, yet no cryptococcal vaccine has progressed to …

Tumor necrosis factor alpha (TNF-α) plays a critical role in the control of cryptococcal
infection, and its insufficiency promotes cryptococcal persistence. To explore the therapeutic …

Cryptococcus species are encapsulated fungi found in the environment that predominantly
cause disease in immunocompromised hosts after inhalation into the lungs. Even with …

Cryptococcus neoformans is a yeast that causes cryptococcosis, a life-threatening disease
that develops following inhalation and dissemination of the organisms. C. neoformans has a …

Cryptococcus neoformans, the etiological agent of cryptococcosis, is an occasional
opportunistic fungal pathogen of immune competent individuals. However, it is a relatively …

The fungal genus Cryptococcus comprises a group of pathogens with considerable
phenotypic and genotypic diversity that can lead to cryptococcosis in both healthy and …