The problem of antibiotic resistance among pathogenic bacteria has reached a crisis level.
The treatment options against infections caused by multiple drug-resistant bacteria are …

ABSTRACT Objective: Overexpression of AcrAB-TolC protein complex is often associated
with the virulence of multidrug-resistant bacteria. Development of an effective efflux pump …

Aim and objective: Overexpression of efflux pumps belonging to the Resistance Nodulation
cell Division (RND) family is the most important intrinsic resistance mechanism of …

Drug resistant bacteria is an increasingly urgent challenge to public health. Bacteria
adaptation and extensive abuse of antibiotics contribute to this dilemma. Active efflux of …

Specific recognition and bacterial adhesion to host cells by uropathogenic Escherichia coli
(UPEC) are the first steps towards infection of epithelial tissue of the human urogenital …

Halogenated 4-hydroxybenzylidene indolinones have been shown to re-sensitize methicillin-
resistant Staphylococcus aureus (MRSA) and vancomycin-resistant Enterococcus faecalis …

Nowadays, antibiotic resistance is a serious problem, especially in countries that have
unregulated use of antibiotics. We aimed to prepare and characterize Sily-Nano from …

Antibiotic resistance is a global threat whose incidences are increasing day by day
worldwide. Thus, there is a need for new chemical entities (NCEs) or exploration of existing …

There is an urgent need to find novel treatments for combating multidrug-resistant bacteria.
Multidrug efflux pumps that expel antibiotics out of cells are major contributors to this …

Regulatory mechanisms for chromosomal genes encoding multidrug resistance (MDR)
efflux pumps (EPs) in Staphylococcus aureus are poorly defined. Microbiological …