Cell shape changes underlie a large set of biological processes ranging from cell division to
cell motility. Stereotyped patterns of cell shape changes also determine tissue remodeling …

During development, mechanical forces cause changes in size, shape, number, position,
and gene expression of cells. They are therefore integral to any morphogenetic processes …

Tissue size, shape, and organization reflect individual cell behaviors such as proliferation,
shape change, and movement. Evidence suggests that mechanical signals operate in …

In development, cells organize into biological tissues through cell growth, migration, and
differentiation. Globally, this process is dictated by a genetically encoded program in which …

D'Arcy Thompson was a proponent of applying mathematical and physical principles to
biological systems, an approach that is becoming increasingly common in developmental …

Embryonic development involves global changes in tissue shape and architecture that are
driven by cell shape changes and rearrangements within cohesive cell sheets …

The generation of organismal form—morphogenesis—arises from forces produced at the
cellular level. In animal cells, much of this force is produced by the actin cytoskeleton. Here …

More than a century ago, it was proposed that mechanical forces could drive tissue
formation. However, only recently with the advent of enabling biophysical and molecular …

Although the shapes of organisms are encoded in their genome, the developmental
processes that lead to the final form of vertebrates involve a constant feedback between …

Morphogenesis is the remarkable process by which cells self-assemble into complex tissues
and organs that exhibit specialized form and function during embryological development …