The abnormal regulation of amyloid-β (Aβ) metabolism (eg, production, cleavage,
clearance) plays a central role in Alzheimer's disease (AD). Among endogenous factors …

Abstract Introduction and Aims Alzheimer's disease (AD) is characterized by the abnormal
accumulation of hyperphosphorylated tau proteins and amyloid‐beta (Aβ) peptides. Recent …

Summary microRNA-132 (miR-132), a known neuronal regulator, is one of the most robustly
downregulated microRNAs (miRNAs) in the brain of Alzheimer's disease (AD) patients …

MicroRNAs are key regulators of transcriptome plasticity and have been implicated with the
pathogenesis of brain diseases. Here, we employed massive parallel sequencing and …

Abstract microRNA‐132 (miR‐132) is involved in prosurvival, anti‐inflammatory and memory‐
promoting functions in the nervous system and has been found consistently downregulated …

Our recent findings link the apolipoprotein E4 (ApoE4)-specific changes in brain
phosphoinositol biphosphate (PIP2) homeostasis to the susceptibility of developing …

Alzheimer's disease (AD) is a progressive neurodegenerative disorder mainly characterized
by amyloid-beta (Aβ) deposition and neurofibrillary tangles (NFTs). The abnormal …

Alzheimer's disease (AD) is a common neurodegenerative disease in the elderly and is the
most common type of dementia. AD is mostly gradual onset, and involves slow, progressive …

Alzheimer's disease (AD) pathogenesis is known to involve a dysregulation of microRNA
expression, and these intricate transcriptional cascades between multiple pathological …

Alzheimer's disease (AD) is a great threat for the health and life of elderly people. MicroRNA-
128 (miR-128) has been reported to be abnormally expressed in the brain of AD patients …