A genetic risk tool for obesity predisposition assessment and personalized nutrition implementation based on macronutrient intake

L Goni, M Cuervo, FI Milagro, JA Martínez - Genes & nutrition, 2015 - Springer
There is little evidence about genetic risk score (GRS)–diet interactions in order to provide
personalized nutrition based on the genotype. The aim of the study was to assess the value …

Whole‐genome approach discovers novel genetic and nongenetic variance components modulated by lifestyle for cardiovascular health

X Zhou, J Van Der Werf… - Journal of the …, 2020 - Am Heart Assoc
Background Both genetic and nongenetic factors can predispose individuals to
cardiovascular risk. Finding ways to alter these predispositions is important for …

Association of dietary patterns and dietary diversity with cardiometabolic disease risk factors among adults in South Asia: The CARRS study

D Kapoor, R Iqbal, K Singh, LM Jaacks… - Asia Pacific journal …, 2018 - search.informit.org
Background and Objectives: To investigate the association of dietary patterns and dietary
diversity with cardiometabolic disease risk factors among South Asians. Methods and Study …

Risk prediction by genetic risk scores for coronary heart disease is independent of self-reported family history

H Tada, O Melander, JZ Louie, JJ Catanese… - European heart …, 2016 - academic.oup.com
Abstract Aims Genetic risk scores (GRSs) have been associated with coronary heart disease
(CHD) in large studies. We asked whether expanding an established 27-variant GRS …

Effect of genetic and environmental influences on cardiometabolic risk factors: a twin study

G Jermendy, T Horváth, L Littvay, R Steinbach… - Cardiovascular …, 2011 - Springer
Background Both genetic and environmental factors play a role in the pathogenesis of type 2
diabetes and cardiovascular diseases. The magnitude of genetic and environmental …

Carbohydrate and sodium intake and physical activity interact with genetic risk scores of four genetic variants mainly related to lipid metabolism to modulate metabolic …

JY Zhou, MY Song, S Park - British Journal of Nutrition, 2019 - cambridge.org
Metabolic syndrome (MetS) risk is influenced by genetic and environmental factors. The
present study explored genetic risk scores (GRS) of genetic variants that influence the MetS …

Interactions of lipid genetic risk scores with estimates of metabolic health in a Danish population

JM Justesen, KH Allin, CH Sandholt… - Circulation …, 2015 - Am Heart Assoc
Background—There are several well-established lifestyle factors influencing dyslipidemia
and currently; 157 genetic susceptibility loci have been reported to be associated with serum …

Healthful plant-based dietary patterns, genetic risk of obesity, and cardiovascular risk in the UK biobank study

Y Heianza, T Zhou, D Sun, FB Hu, L Qi - Clinical Nutrition, 2021 - Elsevier
Background & aims People with a higher genetic risk for obesity are more likely to develop
cardiovascular disease (CVD), and healthy plant-based dietary patterns may be associated …

Ancestry Specific Polygenic Risk Score, Dietary Patterns, Physical Activity, and Cardiovascular Disease

DS Hardy, JT Garvin, TB Mersha - Nutrients, 2024 - mdpi.com
It is unknown whether the impact of high diet quality and physical activity depends on the
level of polygenic risk score (PRS) in different ancestries. Our cross-sectional study utilized …

Joint effect of genetic and lifestyle risk factors on type 2 diabetes risk among Chinese men and women

R Villegas, R Delahanty, YT Gao, J Long, SM Williams… - PloS One, 2012 - journals.plos.org
More than 40 genetic susceptibility loci have been reported for type 2 diabetes (T2D).
Recently, the combined effect of genetic variants has been investigated by calculating a …