Gene–diet interactions in cardiovascular disease

ME Dimitriou, GVZ Dedoussis - Current Nutrition Reports, 2012 - Springer
Cardiovascular disease (CVD), the leading cause of mortality worldwide, results from a
complex interplay between genetic and environmental factors. Genetic studies identified …

Prediction of incident atherosclerotic cardiovascular disease with polygenic risk of metabolic disease: Analysis of 3 prospective cohort studies in Korea

H Song, Y Koh, TM Rhee, SY Choi, S Kang, SP Lee - Atherosclerosis, 2022 - Elsevier
Background and aims Studies have demonstrated that the risk of atherosclerotic
cardiovascular disease (ASCVD) can be assessed by polygenic risk score (PRS) using …

Gene-diet interaction effects on BMI levels in the Singapore Chinese population

X Chang, R Dorajoo, Y Sun, Y Han, L Wang, CC Khor… - Nutrition journal, 2018 - Springer
Background Recent genome-wide association studies (GWAS) have identified 97 body-
mass index (BMI) associated loci. We aimed to evaluate if dietary intake modifies BMI …

A composite scoring of genotypes discriminates coronary heart disease risk beyond conventional risk factors in the Boston Puerto Rican Health Study

M Junyent, KL Tucker, J Shen, YC Lee… - Nutrition, Metabolism …, 2010 - Elsevier
BACKGROUND AND AIMS: Using a genetic predisposition score (GPS), integrating the
additive associations of a set of single nucleotide polymorphisms (SNPs) with CHD, we …

Genetic risk sum score comprised of common polygenic variation is associated with body mass index

RE Peterson, HH Maes, P Holmans, AR Sanders… - Human genetics, 2011 - Springer
Genome-wide association studies (GWAS) of body mass index (BMI) using large samples
have yielded approximately a dozen robustly associated variants and implicated additional …

Interaction between vascular endothelial growth factor-A (rs2010963) gene polymorphisms and dietary diversity score on cardiovascular risk factors in patients with …

M Abbasalizad Farhangi, M Vajdi, L Nikniaz… - Lifestyle …, 2020 - karger.com
Background: The vascular endothelial growth factor-A (VEGFA) family of cytokines regulates
proliferation, angiogenesis, and migration of endothelial cells, increases vascular …

Effects of Mediterranean diets and nutrigenomics on cardiovascular health

S Bakrim, S Aboulaghras, T Aanniz… - Critical Reviews in …, 2023 - Taylor & Francis
The field of nutrigenomics studies the interaction between nutrition and genetics, and how
certain dietary patterns can impact gene expression and overall health. The Mediterranean …

Saturated fat intake modulates the association between an obesity genetic risk score and body mass index in two US populations

P Casas-Agustench, DK Arnett, CE Smith… - Journal of the Academy …, 2014 - Elsevier
Combining multiple genetic variants related to obesity into a genetic risk score (GRS) might
improve identification of individuals at risk of developing obesity. Moreover, characterizing …

Associations between dietary animal and plant protein intake and cardiometabolic risk factors—a cross-sectional study in China Health and Nutrition Survey

S Meng, Z Cui, M Li, T Li, F Wu, T Kang, H Meng - Nutrients, 2021 - mdpi.com
Available data investigating the associations between dietary animal and plant protein
intakes and cardiometabolic risk factors (CMRFs) among populations with habitual plant …

[HTML][HTML] Isocaloric substitution of plant-based protein for animal-based protein and cardiometabolic risk factors in a multiethnic Asian population

YQ Lee, A Chia, C Whitton, D Cameron-Smith… - The Journal of …, 2023 - Elsevier
Background Evidence is accumulating that intake of animal-based and plant-based proteins
has different effects on cardiometabolic health, but less is known about the health effect of …