Association of genome-wide polygenic risk score for body mass index with cardiometabolic health from childhood through midlife
M Shi, W Chen, X Sun, LA Bazzano, J He… - Circulation: Genomic …, 2022 - Am Heart Assoc
Background: Genetic information may help to identify individuals in childhood who are at
increased risk for cardiometabolic disease. Methods: We included 1201 BHS (Bogalusa …
increased risk for cardiometabolic disease. Methods: We included 1201 BHS (Bogalusa …
Transferability of genetic loci and polygenic scores for cardiometabolic traits in British Pakistanis and Bangladeshis
Abstract Background Individuals with South Asian ancestry have higher risk of heart disease
than other groups in Western countries; however, most genetic research has focused on …
than other groups in Western countries; however, most genetic research has focused on …
The Mediterranean diet reduces the genetic risk of chromosome 9p21 for myocardial infarction in an Asian population community cohort
HB Leu, CM Chung, JW Chen, WH Pan - Scientific reports, 2019 - nature.com
The interaction of genetic susceptibility and dietary habits in cardiovascular disease (CVD)
remains undetermined. The purpose of this study was to investigate whether a …
remains undetermined. The purpose of this study was to investigate whether a …
Single nucleotide polymorphisms (SNPs) involved in insulin resistance, weight regulation, lipid metabolism and inflammation in relation to metabolic syndrome: an …
CM Povel, JMA Boer, NC Onland-Moret… - Cardiovascular …, 2012 - Springer
Background Mechanisms involved in metabolic syndrome (MetS) development include
insulin resistance, weight regulation, inflammation and lipid metabolism. Aim of this study is …
insulin resistance, weight regulation, inflammation and lipid metabolism. Aim of this study is …
[HTML][HTML] Genetic identification for non-communicable disease: Findings from 20 years of the Tehran Lipid and Glucose Study
MS Daneshpour, M Hedayati… - … of endocrinology and …, 2018 - ncbi.nlm.nih.gov
Results This review summarizes associations of 6 binary phenotypes and 17 quantitative
traits with genetic markers in 26 genes. Of the 47 genetic markers, studied most were related …
traits with genetic markers in 26 genes. Of the 47 genetic markers, studied most were related …
Use of a gene score of multiple low-modest effect size variants can predict the risk of obesity better than the individual SNPs
Background Obesity is a complex disorder, the development of which is modulated by a
multitude of environmental, behavioral and genetic factors. The common forms of obesity are …
multitude of environmental, behavioral and genetic factors. The common forms of obesity are …
Multiple metabolic genetic risk scores and type 2 diabetes risk in three racial/ethnic groups
YC Klimentidis, NE Wineinger… - The Journal of …, 2014 - academic.oup.com
Context/Rationale: Meta-analyses of genome-wide association studies have identified many
single-nucleotide polymorphisms associated with various metabolic and cardiovascular …
single-nucleotide polymorphisms associated with various metabolic and cardiovascular …
Physical activity, smoking, and genetic predisposition to obesity in people from Pakistan: the PROMIS study
Background Multiple genetic variants have been reliably associated with obesity-related
traits in Europeans, but little is known about their associations and interactions with lifestyle …
traits in Europeans, but little is known about their associations and interactions with lifestyle …
Cardio-metabolic disease genetic risk factors among Māori and Pacific Island people in Aotearoa New Zealand: current state of knowledge and future directions
TR Merriman, PL Wilcox - Annals of Human Biology, 2018 - Taylor & Francis
Context: Cardio-metabolic conditions in Aotearoa New Zealand (NZ) Māori and non-
indigenous Polynesian (Pacific) populations have been increasing in prevalence and …
indigenous Polynesian (Pacific) populations have been increasing in prevalence and …
Application of single-nucleotide polymorphism-related risk estimates in identification of increased genetic susceptibility to cardiovascular diseases: a literature review
S Fiatal, R Adany - Frontiers in public health, 2018 - frontiersin.org
Background Although largely preventable, cardiovascular diseases (CVDs) are the biggest
cause of death worldwide. Common complex cardiovascular disorders (eg, coronary heart …
cause of death worldwide. Common complex cardiovascular disorders (eg, coronary heart …