Oxidative stress and antioxidants in neurodegenerative disorders

EO Olufunmilayo, MB Gerke-Duncan, RMD Holsinger - Antioxidants, 2023 - mdpi.com
Neurodegenerative disorders constitute a substantial proportion of neurological diseases
with significant public health importance. The pathophysiology of neurodegenerative …

An overview of oxidative stress, neuroinflammation, and neurodegenerative diseases

DM Teleanu, AG Niculescu, II Lungu, CI Radu… - International journal of …, 2022 - mdpi.com
Oxidative stress has been linked with a variety of diseases, being involved in the debut
and/or progress of several neurodegenerative disorders. This review intends to summarize …

Mechanism of oxidative stress in neurodegeneration

S Gandhi, AY Abramov - Oxidative medicine and cellular …, 2012 - Wiley Online Library
Biological tissues require oxygen to meet their energetic demands. However, the
consumption of oxygen also results in the generation of free radicals that may have …

Oxidative stress in neurodegenerative diseases: from molecular mechanisms to clinical applications

Z Liu, T Zhou, AC Ziegler, P Dimitrion… - Oxidative medicine and …, 2017 - Wiley Online Library
Increasing numbers of individuals, particularly the elderly, suffer from neurodegenerative
disorders. These diseases are normally characterized by progressive loss of neuron cells …

Antioxidants as treatment for neurodegenerative disorders

B Moosmann, C Behl - Expert opinion on investigational drugs, 2002 - Taylor & Francis
Oxidative stress is a ubiquitously observed hallmark of neurodegenerative disorders.
Neuronal cell dysfunction and cell death due to oxidative stress may causally contribute to …

Oxidative stress in neurodegenerative diseases: from a mitochondrial point of view

G Cenini, A Lloret, R Cascella - Oxidative medicine and …, 2019 - Wiley Online Library
Age is the main risk factor for a number of human diseases, including neurodegenerative
disorders such as Alzheimer's disease, Parkinson's disease, and amyotrophic lateral …

Oxidative stress and the pathogenesis of neurodegenerative disorders

A Reynolds, C Laurie, RL Mosley… - International review of …, 2007 - Elsevier
Microglia‐derived inflammatory neurotoxins play a principal role in the pathogenesis of
neurodegenerative disorders including Alzheimer's disease, Parkinson's disease …

Is modulation of oxidative stress an answer? The state of the art of redox therapeutic actions in neurodegenerative diseases

V Chiurchiù, A Orlacchio… - Oxidative medicine and …, 2016 - Wiley Online Library
The central nervous system is particularly sensitive to oxidative stress due to many reasons,
including its high oxygen consumption even under basal conditions, high production of …

Oxidative stress: a key modulator in neurodegenerative diseases

A Singh, R Kukreti, L Saso, S Kukreti - Molecules, 2019 - mdpi.com
Oxidative stress is proposed as a regulatory element in ageing and various neurological
disorders. The excess of oxidants causes a reduction of antioxidants, which in turn produce …

Roles of oxidative stress in synaptic dysfunction and neuronal cell death in Alzheimer's disease

G Plascencia-Villa, G Perry - Antioxidants, 2023 - mdpi.com
Alzheimer's disease (AD) is a brain disorder that progressively undermines memory and
thinking skills by affecting the hippocampus and entorhinal cortex. The main …