Although medical opinions are gradually converging, there is still no firm consensus
regarding the appropriate ventilatory management of acute lung injury (ARDS). The high …

A growing body of experimental and clinical literature underscores the importance of
preserving alveolar patency within the acutely injured lung. Persistent collapse delays the …

Partial liquid ventilation--the future is now. - Abstract - Europe PMC Sign in | Create an
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Background: We previously demonstrated a markedly dependent distribution of ventilator-
induced lung injury in oleic acid-injured supine animals ventilated with large tidal volumes …

The concept of liquid breathing by land animals is extremely counterintuitive and virtually
oxymoronic. The notion of liquid breathing became possible in the 1940s, however, with the …

OBJECTIVES: Head-elevated body positioning, a default clinical practice, predictably
increases end-expiratory transpulmonary pressure and aerated lung volume. In acute …

Patients with the acute respira-tory distress syndrome (ARDS) often need mechanical
ventilation to unload the failing respiratory muscles, restore adequate oxygenation, and buy …

Objective Partial liquid ventilation with the perfluorochemical, perflubron, has been shown to
improve lung mechanics and enhance gas exchange in the treatment of severe acute lung …

Current ventilator strategies aim at maintaining an open lung and limiting both peak
inspiratory pressures and tidal volumes to avoid alveolar distension. Perfluorocarbons, as …

Patients with the acute respira-tory distress syndrome (ARDS) often need mechanical
ventilation to unload the failing respiratory muscles, restore adequate oxygenation, and buy …