Influence of age or circadian time on bcl-2 and bax mRNA expression in the rat hippocampus after corticosterone exposure
A Yoshimura, A Masui, S Jinde, H Kanai, N Kato… - Brain research …, 2007 - Elsevier
A rapid elevation in the level of endogenous corticosterone (CORT) functions in the stress
response associated with the hypothalamus–pituitary–adrenal axis, and it has been well …
response associated with the hypothalamus–pituitary–adrenal axis, and it has been well …
Corticosterone differentially regulates bax, bcl-2 and bcl-x mRNA levels in the rat hippocampus
It has previously been shown that adrenalectomy (ADX) produces apoptosis in the granule
cell of the dentate gyrus (DG), and that this effect is prevented by corticosterone …
cell of the dentate gyrus (DG), and that this effect is prevented by corticosterone …
Corticosterone impairs hippocampal neuronal calcium regulation—possible mediating mechanisms
EM Elliott, RM Sapolsky - Brain research, 1993 - Elsevier
Corticosterone (CORT), the predominant glucocorticoid of rats which is secreted during
stress, increases hippocampal neuronal vulnerability to excitotoxins, hypoxia-ischemia, and …
stress, increases hippocampal neuronal vulnerability to excitotoxins, hypoxia-ischemia, and …
Similar effects of aging and corticosterone treatment on mouse hippocampal function
M Talmi, E Carlier, B Soumireu-Mourat - Neurobiology of aging, 1993 - Elsevier
Cumulative exposure to corticosterone (CORT) during the lifespan plays an important role in
the hippocampal aging process, and similar disturbances have been observed in chronic …
the hippocampal aging process, and similar disturbances have been observed in chronic …
Chronic corticosterone affects brain weight, and mitochondrial, but not glial volume fraction in hippocampal area CA3
PS Coburn-Litvak, DA Tata, HE Gorby, DP McCloskey… - Neuroscience, 2004 - Elsevier
Corticosterone (CORT), the predominant glucocorticoid in rodents, is known to damage
hippocampal area CA3. Here we investigate how that damage is represented at the cellular …
hippocampal area CA3. Here we investigate how that damage is represented at the cellular …
Aging increases basal but not stress-induced levels of corticosterone in the brain of the awake rat
P Garrido, M de Blas, A Del Arco, G Segovia… - Neurobiology of …, 2012 - Elsevier
The main purpose of this study was to evaluate the effect of aging on plasma and free
corticosterone (CORT) levels in the brain (hippocampus and prefrontal cortex) in basal …
corticosterone (CORT) levels in the brain (hippocampus and prefrontal cortex) in basal …
Attenuating corticosterone levels on the day of memory assessment prevents chronic stress‐induced impairments in spatial memory
RL Wright, EN Lightner, JS Harman… - European Journal of …, 2006 - Wiley Online Library
This study investigated whether chronic stress‐induced spatial memory deficits were caused
by changes in the hypothalamic‐pituitary‐adrenal axis, such as corticosterone (CORT) …
by changes in the hypothalamic‐pituitary‐adrenal axis, such as corticosterone (CORT) …
Intrahippocampal corticosterone response in mice selectively bred for extremes in stress reactivity: a microdialysis study
JM Heinzmann, CK Thoeringer… - Journal of …, 2010 - Wiley Online Library
The hypothalamic‐pituitary‐adrenocortical (HPA) axis is one of the major stress hormone
systems, and glucocorticoids (GCs) play a pivotal role in homeostatic processes throughout …
systems, and glucocorticoids (GCs) play a pivotal role in homeostatic processes throughout …
Chronic corticosterone administration from adolescence through early adulthood attenuates depression-like behaviors in mice
Z Xu, Y Zhang, B Hou, Y Gao, Y Wu, C Zhang - Journal of affective …, 2011 - Elsevier
There is evidence that depression may have a different neural basis at different ages.
Although chronic stress and elevated glucocorticoid levels have been demonstrated to lead …
Although chronic stress and elevated glucocorticoid levels have been demonstrated to lead …
Glucocorticoid-dependent hippocampal transcriptome in male rats: pathway-specific alterations with aging
KC Chen, EM Blalock, MA Curran-Rauhut… - …, 2013 - academic.oup.com
Although glucocorticoids (GCs) are known to exert numerous effects in the hippocampus,
their chronic regulatory functions remain poorly understood. Moreover, evidence is …
their chronic regulatory functions remain poorly understood. Moreover, evidence is …
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