[PDF][PDF] Acquired APC resistance and oral contraceptives: a randomised cross-over study of two low dose oral contraceptives

J Rosing, S Middeldorp, J Curvers, M Thomassen… - Lancet, 1999 - researchgate.net
Background: Background: We have reported previously that, compared with use of second
generationn oral contraceptives, the use of third generation oral contraceptives iss …

Low-dose oral contraceptives and acquired resistance to activated protein C: a randomised cross-over study

J Rosing, S Middeldorp, J Curvers, MCL GDlig… - The Lancet, 1999 - thelancet.com
Background We have reported previously that, compared with use of second-generation oral
contraceptives, the use of third-generation oral contraceptives is associated with increased …

Hormone replacement therapy and acquired resistance to activated protein C: results of a randomized, double‐blind, placebo‐controlled trial

E Høibraaten, MC Mowinckel… - British journal of …, 2001 - Wiley Online Library
Recent studies suggest that low‐dose oral contraceptives may cause acquired resistance to
activated protein C (APC). The aims of this study were to determine whether hormone …

Importance of levonorgestrel dose in oral contraceptives for effects on coagulation

C Kluft, MPM De Maat, LAJ Heinemann, M Spannagl… - The Lancet, 1999 - thelancet.com
Combined oral contraceptives show clear differences in effect on the tissue factor-initiated
coagulation test of activated protein C resistance, which is dependent on the presence and …

APC resistance and third-generation oral contraceptives: Acquired resistance to activated protein C, oral contraceptives and the risk of thromboembolic disease

JC Gris, C Jamin, JL Benifla, I Quere… - Human …, 2001 - academic.oup.com
Using a newly-developed technique, a severe acquired plasma resistance to activated
protein C has been described in women using third-generation (rather than second …

[HTML][HTML] Impact of progestagens on activated protein C (APC) resistance among users of oral contraceptives

M Alhenc‐Gelas, G Plu‐Bureau, S Guillonneau… - Journal of thrombosis …, 2004 - Elsevier
Oral contraceptive (OC) use is associated with an increased risk of venous
thromboembolism. Previous data reported higher thrombotic risk in women using third …

Acquired APC resistance and oral contraceptives: differences between two functional tests

J Curvers, MCLGD Thomassen… - British journal of …, 1999 - Wiley Online Library
Resistance to activated protein C (APC) is often associated with a mutation in factor V (factor
VLeiden). Individuals without factor VLeiden who exhibit a response in functional APC …

Activated protein C resistance determined with a thrombin generation‐based test predicts for venous thrombosis in men and women

G Tans, A van Hylckama Vlieg… - British journal of …, 2003 - Wiley Online Library
Activated protein C (APC) resistance, determined with a thrombin‐generation‐based APC
resistance test, may explain risk differences of venous thrombosis in users of second‐and …

Resistance to activated protein C in women using oral contraceptives

M Spannagl, A Dick, A Assmann… - … in thrombosis and …, 1998 - thieme-connect.com
Resistance to activated protein C (APC resistance) is an important and common risk factor
for deep vein thrombosis. The majority of patients with APC resistance carry a mutation on …

[HTML][HTML] Different effects of oral contraceptives containing different progestogens on protein S and tissue factor pathway inhibitor

H Van Vliet, RM Bertina, AEA Dahm… - Journal of Thrombosis …, 2008 - Elsevier
Background: Oral contraceptives (OC) containing different types of progestogens induce
different sensitivities to activated protein C (APC) measured with the thrombin generation …