Cytokines released by T lymphocytes activated in the course of sarcoidosis, eg, interleukin-2
(IL-2) and interferon-gamma (IFN-gamma), indicate the presence of Th1 cells leading to the …

The pathogenesis of pulmonary sarcoidosis has been related to an increased production of
Th1-like cytokines. However, cytokine expression in sarcoidosis has not been systematically …

BACKGROUND Pulmonary sarcoidosis is characterised by a mononuclear alveolitis with a
predominance of CD4+ T cells and macrophages. We determined the intracellular …

In pulmonary sarcoidosis, activated T cells accumulate in the lungs. We hypothesized that
the balance between the T-helper type 1 (Th1) cytokines (interferon [IFN]-γ and interleukin …

Background: Sarcoidosis is thought to be a type-1 cytokine-mediated disorder. However, few
data are available on the profiles of cytokine expression by TH cells at the single-cell level …

Pulmonary sarcoidosis is a disease characterized by increased numbers of T-lymphocytes
in the alveolar structures, which through the production of lymphokines modulate granuloma …

Objectives. The balance between Th1 and Th2 T cells, classified by virtue of their cytokine
production can in an immune response influence the phenotype and progression of several …

Different lymphocyte subpopulations have been evaluated in bronchoalveolar fluid and
blood obtained from six patients with active and six with inactive pulmonary sarcoidosis and …

In this study, we have investigated the balance between Th1‐and Th2‐like activity in the
lungs in sarcoidosis and have determined the effect of corticosteroid treatment on this …

Background Sarcoidosis is thought to be a T-helper type 1 cytokine (Th2 cytokine) mediated
disorder. Induced sputum (IS) has been proposed as a useful non-invasive method, mainly …