Abstract Small fibres constitute 70–90% of peripheral nerve fibres and regulate several key
functions such as tissue blood flow, temperature and pain perception as well as sweating, all …

Surrogate markers of diabetic neuropathy are being actively sought to facilitate the
diagnosis, measure the progression, and assess the benefits of therapeutic intervention in …

Aims To assess small‐fibre involvement in diabetic patients with neuropathic pain. Methods
Peripheral nerve function was assessed in 30 patients with Type 2 diabetes mellitus (T2DM …

OBJECTIVE Quantitative assessment of small fiber damage is key to the early diagnosis and
assessment of progression or regression of diabetic sensorimotor polyneuropathy (DSPN) …

Objectives Corneal confocal microscopy (CCM) is a rapid, non-invasive, reproducible
technique that quantifies small nerve fibres. We have compared the diagnostic capability of …

Diabetic peripheral neuropathy (DPN) is diagnosed too late, which contrasts with our
approach for diabetic retinopathy and nephropathy, where incipient disease is detected …

Diabetic neuropathy is a prevalent microvascular complication of diabetes mellitus, affecting
nerves in all parts of the body including corneal nerves and peripheral nervous system …

Diabetic polyneuropathy, which is a chronic symmetrical length‐dependent sensorimotor
polyneuropathy, is the most common form of diabetic neuropathy. Although diabetic …

We sought to determine whether early nerve damage may be detected by corneal confocal
microscopy (CCM), skin biopsy, and neurophysiological tests in 86 recently diagnosed type …

Small fiber neuropathy (SFN) is characterized by negative sensory symptoms (thermal and
pinprick hypoesthesia) reflecting peripheral deafferentation and positive sensory symptoms …