Background: A major global health issue is the existence of chronic wounds. Appropriate
diagnosis and treatment is essential to promote wound healing and prevent further …

Significance: Chronic wounds include, but are not limited, to diabetic foot ulcers, venous leg
ulcers, and pressure ulcers. They are a challenge to wound care professionals and …

Non-healing chronic wounds present a major biological, psychological, social, and financial
burden on both individual patients and the broader health system. Pathologically extensive …

Chronic inflammation is one of the hallmarks of chronic wounds and is tightly coupled to
immune regulation. The dysregulation of the immune system leads to continuing …

Introduction: About 2% of the Western world population suffer from chronic wounds, resulting
from underlying disorders (eg, diabetes, excessive pressure, vascular insufficiencies and …

Chronic Wounds. Wounds throughout the body are common and can be debilitating injuries
with long recovery times. 1− 3 Wounds that fail to proceed through the normal phases of …

Every year, millions of people experience burns, suffer from nonhealing wounds, or have
acute wounds that become complicated by infection, dehiscence or problematic scarring …

Wound healing is highly specialized dynamic multiple phase process for the repair of
damaged/injured tissues through an intricate mechanism. Any failure in the normal wound …

Background Wound treatment comprises a substantial portion of the healthcare budgets in
developed countries. Studies suggest that about 50% of patients admitted to hospitals have …

Chronic wounds are characterized by their inability to heal within an expected time frame
and have emerged as an increasingly important clinical problem over the past several …