Piperacillin/tazobactam (TZP) as an alternative treatment to carbapenems for infections
involving extended-spectrum β-lactamase (ESBL)-producing Enterobacteriaceae (ESBL-PE) …

Urinary tract infections caused by multidrug-resistant Enterobacteriaceae are a growing
burden worldwide. Recent studies of urinary pharmacokinetics described high piperacillin …

Carbapenems are recommended for the treatment of urosepsis caused by extended-
spectrum β-lactamase (ESBL)-producing, multidrug-resistant Escherichia coli; however, due …

Background: Carbapenems are the drug of choice for treatment of infections due to
extended-spectrum beta-lactamase (ESBL)-producing Enterobacteriaceae. Current …

Extended-spectrum β-lactamase (ESBL)-producing Enterobacteriaceae pose a huge threat
to human health, especially in the context of complicated urinary tract infections (cUTIs) …

Background Urosepsis caused by extended-spectrum β-lactamase (ESBL)-producing
Escherichia coli is increasing worldwide. Carbapenems are commonly recommended for the …

Piperacillin-tazobactam has been proposed as an alternative to carbapenems for the
treatment of infections caused by extended-spectrum-β-lactamase (ESBL)-producing …

Background Limited data exist regarding the efficacy of piperacillin-tazobactam (TZP) for the
management of nonbacteremic pyelonephritis caused by extended-spectrum β-lactamase …

The pharmacodynamics of piperacillin/tazobactam and cefepime were evaluated against
extended-spectrum β-lactamase (ESBL)-producing organisms. Ten thousand patients were …

Piperacillin/tazobactam (TZP) is administered intravenously in a fixed ratio (8: 1) with the
potential for inadequate tazobactam exposure to ensure piperacillin activity against …