Neuroinflammation has been implicated in multiple brain disorders but the extent and the
magnitude of change in immune-related genes (IRGs) across distinct brain disorders has not …

Understanding the pathophysiological mechanisms of neuropsychiatric disorders has been
a challenging quest for neurobiologists. Recent years have witnessed enormous …

Background This study undertakes a systematic and comprehensive analysis of brain gene
expression profiles of immune/inflammation-related genes in aging and Alzheimer's disease …

Although some existing epidemiological observations and molecular experiments
suggested that brain disorders in the realm of psychiatry may be influenced by immune …

Background Immune system dysfunction has been proven to be an important pathological
event in Alzheimer's disease (AD). Mild cognitive impairment (MCI), as a transitional stage …

Abstract The Stanley Neuropathology Consortium Integrative Database (SNCID, http://sncid.
stanleyresearch. org) is a data-mining tool that includes 379 neuropathology data sets from …

Parkinson's disease (PD) is an age-related and second most common neurodegenerative
disorder. In recent years, increasing evidence revealed that peripheral immune cells might …

Using gene microarray technology, we found that inflammation in the central nervous system
(CNS) not only induced the expression of many immune-related genes, but also significantly …

Immune infiltration of peripheral natural killer (NK) cells in the brain has been observed in
Alzheimer's disease (AD). Immunity-related genes (IRGs) play an essential role in immune …

Background: Parkinson's disease (PD) is a common, age-related, and progressive
neurodegenerative disease. Growing evidence indicates that immune dysfunction plays an …