Currently, there is a lack of effective medicines capable of halting or reversing the
progression of neurodegenerative disorders, including amyotrophic lateral sclerosis …

As the population ages, the incidence of neurodegenerative diseases is increasing. Due to
intensive research, important steps in the elucidation of pathogenetic cascades have been …

A growing body of evidence suggests the alteration of the reduction-oxidation (redox)
homeostasis in the brain grown with the increasing of the age. The brain is composed of …

Fundamental organelles that occur in every cell type with the exception of mammal
erythrocytes, the mitochondria are required for multiple pivotal processes that include the …

Neurodegenerative diseases such as Alzheimer's disease, Parkinson's disease,
Huntington's disease, and amyotrophic lateral sclerosis are a heterogeneous group of …

In this review, the relationship between bioenergetics, mitochondrial dysfunction, and
inflammation will be and how they contribute to neurodegeneration, specifically in …

Neurodegenerative diseases (NDs) such as Alzheimer disease (AD), Parkinson disease
(PD), and Huntington disease (HD) represent a major socio-economic challenge in view of …

The world's population aging progression renders age‐related neurodegenerative diseases
to be one of the biggest unsolved problems of modern society. Despite the progress in …

Mitochondria are multifaceted organelles that serve to power critical neuronal functions.
Additionally, mitochondria buffer calcium, produce intracellular reactive oxygen species …

Bioenergetic and mitochondrial dysfunction are common hallmarks of neurodegenerative
diseases. Decades of research describe how genetic and environmental factors initiate …