Despite advances in uncovering the mechanisms that underlie neuroinflammation and
neurodegenerative disease, therapies that prevent neuronal loss remain elusive. Targeting …

Astrocyte reactivity is a hallmark of neuroinflammation that arises with Alzheimer's disease
(AD) and nearly every other neurodegenerative condition. While astrocytes certainly …

Astrocytes play crucial roles in the brain and are involved in the neuroinflammatory
response. They become reactive in response to virtually all pathological situations in the …

Classically, the loss of vulnerable neuronal populations in neurodegenerative diseases was
considered to be the consequence of cell autonomous degeneration of neurons. However …

Astrocytes regulate fundamentally important functions to maintain central nervous system
(CNS) homeostasis. Altered astrocytic function is now recognized as a primary contributing …

Alzheimer's disease (AD) is a chronic and fatal disease, in which neuronal damage at its late
stage cannot be easily reversed. Because AD progression is caused by multiple factors …

Astrocyte heterogeneity is a rapidly evolving field driven by innovative techniques.
Inflammatory astrocytes, one of the first described subtypes of reactive astrocytes, are …

Astrocytes, one of the largest glial cell population in the central nervous system (CNS), play
a key function in several events of brain development and function, such as synapse …

Astrocytes control multiple processes in the nervous system in health and disease. It is now
clear that specific astrocyte subsets or activation states are associated with specific genomic …

Astrocytes play important roles in numerous central nervous system disorders including
autoimmune inflammatory, hypoxic, and degenerative diseases such as Multiple Sclerosis …