An inventory of the Aspergillus niger secretome by combining in silico predictions with shotgun proteomics data

M Braaksma, ES Martens-Uzunova, PJ Punt… - BMC genomics, 2010 - Springer
Background The ecological niche occupied by a fungal species, its pathogenicity and its
usefulness as a microbial cell factory to a large degree depends on its secretome. Protein …

Compositions of fungal secretomes indicate a greater impact of phylogenetic history than lifestyle adaptation

JJ Krijger, MR Thon, HB Deising, SGR Wirsel - BMC genomics, 2014 - Springer
Background Since the first fungal genome sequences became available, investigators have
been employing comparative genomics to understand how fungi have evolved to occupy …

Genome-scale analysis of the high-efficient protein secretion system of Aspergillus oryzae

L Liu, A Feizi, T Österlund, C Hjort, J Nielsen - BMC Systems Biology, 2014 - Springer
Abstract Background The koji mold, Aspergillus oryzae is widely used for the production of
industrial enzymes due to its particularly high protein secretion capacity and ability to …

Evaluation of secretion prediction highlights differing approaches needed for oomycete and fungal effectors

J Sperschneider, AH Williams, JK Hane… - Frontiers in plant …, 2015 - frontiersin.org
The steadily increasing number of sequenced fungal and oomycete genomes has enabled
detailed studies of how these eukaryotic microbes infect plants and cause devastating …

Improved prediction of fungal effector proteins from secretomes with EffectorP 2.0

J Sperschneider, PN Dodds… - Molecular plant …, 2018 - Wiley Online Library
Plant‐pathogenic fungi secrete effector proteins to facilitate infection. We describe extensive
improvements to EffectorP, the first machine learning classifier for fungal effector prediction …

An automated and combinative method for the predictive ranking of candidate effector proteins of fungal plant pathogens

DAB Jones, L Rozano, JW Debler, RL Mancera… - Scientific reports, 2021 - nature.com
Fungal plant-pathogens promote infection of their hosts through the release of 'effectors'—a
broad class of cytotoxic or virulence-promoting molecules. Effectors may be recognised by …

The Predicted Secretome of the Plant Pathogenic Fungus Fusarium graminearum: A Refined Comparative Analysis

NA Brown, J Antoniw, KE Hammond-Kosack - PloS one, 2012 - journals.plos.org
The fungus Fusarium graminearum forms an intimate association with the host species
wheat whilst infecting the floral tissues at anthesis. During the prolonged latent period of …

Computational prediction of effector proteins in fungi: opportunities and challenges

H Sonah, RK Deshmukh, RR Bélanger - Frontiers in plant science, 2016 - frontiersin.org
Effector proteins are mostly secretory proteins that stimulate plant infection by manipulating
the host response. Identifying fungal effector proteins and understanding their function is of …

Fungal secretome profile categorization of CAZymes by function and family corresponds to fungal phylogeny and taxonomy: Example Aspergillus and Penicillium

K Barrett, K Jensen, AS Meyer, JC Frisvad, L Lange - Scientific reports, 2020 - nature.com
Fungi secrete an array of carbohydrate-active enzymes (CAZymes), reflecting their
specialized habitat-related substrate utilization. Despite its importance for fitness, enzyme …

Defining the Predicted Protein Secretome of the Fungal Wheat Leaf Pathogen Mycosphaerella graminicola

A Morais do Amaral, J Antoniw, JJ Rudd… - PLoS …, 2012 - journals.plos.org
The Dothideomycete fungus Mycosphaerella graminicola is the causal agent of Septoria
tritici blotch, a devastating disease of wheat leaves that causes dramatic decreases in yield …