The biology of cytomegalovirus drug resistance
M Hakki, S Chou - Current opinion in infectious diseases, 2011 - journals.lww.com
An increasing volume of information correlating CMV genotypes and drug susceptibility
phenotypes is becoming available. This will improve the interpretation of sequence-based …
phenotypes is becoming available. This will improve the interpretation of sequence-based …
The genetic basis of human cytomegalovirus resistance and current trends in antiviral resistance analysis
SH James, MN Prichard - Infectious Disorders-Drug Targets …, 2011 - ingentaconnect.com
Infections due to resistant human cytomegalovirus (CMV) are an emerging problem,
particularly in immunocompromised hosts. When managing such patients, clinicians should …
particularly in immunocompromised hosts. When managing such patients, clinicians should …
A new tool linking human cytomegalovirus drug resistance mutations to resistance phenotypes
M Chevillotte, J von Einem, BM Meier, FM Lin… - Antiviral research, 2010 - Elsevier
Drug resistant strains of human cytomegalovirus (HCMV) in patients at risk may increasingly
develop into a problem in the clinical setting. Genotypic resistance testing is becoming the …
develop into a problem in the clinical setting. Genotypic resistance testing is becoming the …
Detection of cytomegalovirus drug resistance mutations by next-generation sequencing
MK Sahoo, MI Lefterova, F Yamamoto… - Journal of clinical …, 2013 - Am Soc Microbiol
Antiviral therapy for cytomegalovirus (CMV) plays an important role in the clinical
management of solid organ and hematopoietic stem cell transplant recipients. However …
management of solid organ and hematopoietic stem cell transplant recipients. However …
Antiviral drug resistance of human cytomegalovirus
NS Lurain, S Chou - Clinical microbiology reviews, 2010 - Am Soc Microbiol
The study of human cytomegalovirus (HCMV) antiviral drug resistance has enhanced
knowledge of the virological targets and the mechanisms of antiviral activity. The currently …
knowledge of the virological targets and the mechanisms of antiviral activity. The currently …
Antiviral drug resistance in human cytomegalovirus
S Chou - Transplant infectious disease, 1999 - Wiley Online Library
Drug‐resistant cytomegalovirus (CMV) should be considered when viral shedding persists
after several weeks of therapy. The problem is most likely to arise in the setting of a severely …
after several weeks of therapy. The problem is most likely to arise in the setting of a severely …
Advances in the genotypic diagnosis of cytomegalovirus antiviral drug resistance
S Chou - Antiviral research, 2020 - Elsevier
Cytomegalovirus (CMV) drug resistance mutation maps are updated with recent information
for polymerase inhibitors, the terminase inhibitor letermovir and the UL97 kinase inhibitor …
for polymerase inhibitors, the terminase inhibitor letermovir and the UL97 kinase inhibitor …
Approach to drug-resistant cytomegalovirus in transplant recipients
S Chou - Current opinion in infectious diseases, 2015 - journals.lww.com
Technical advancements can enhance the accurate and timely genotypic detection of drug
resistance. Antivirals undergoing clinical trial offer the prospect of new viral targets and drug …
resistance. Antivirals undergoing clinical trial offer the prospect of new viral targets and drug …
Phenotyping of cytomegalovirus drug resistance mutations by using recombinant viruses incorporating a reporter gene
S Chou, LC Van Wechel, HM Lichy… - Antimicrobial agents …, 2005 - Am Soc Microbiol
ABSTRACT A new recombinant phenotyping method was developed for the analysis of drug
resistance mutations in human cytomegalovirus (CMV). CMV strain T2211 was derived from …
resistance mutations in human cytomegalovirus (CMV). CMV strain T2211 was derived from …
Resistance of human cytomegalovirus to antiviral drugs
A Erice - Clinical Microbiology Reviews, 1999 - Am Soc Microbiol
Resistance of cytomegalovirus (CMV) to antiviral agents is a well-recognized phenomenon
that has been observed in the laboratory and in the clinical setting. Infections caused by …
that has been observed in the laboratory and in the clinical setting. Infections caused by …