Recognition of infected cells by natural killer cells

LN Carayannopoulos, WM Yokoyama - Current opinion in immunology, 2004 - Elsevier
Under the influence of cytokines associated with innate immunity, natural killer (NK) cells
rapidly become activated and migrate to sites of infection. Upon contact with infected …

Natural killer cells and viral infections

AR French, WM Yokoyama - Current opinion in immunology, 2003 - Elsevier
Natural killer (NK) cells play a key role in innate host defense against viruses. Significant
progress has been made in understanding the specific response of NK cells during viral …

Activation of natural killer cells during microbial infections

A Horowitz, KA Stegmann, EM Riley - Frontiers in immunology, 2012 - frontiersin.org
Natural killer (NK) cells are large granular lymphocytes that express a diverse array of
germline encoded inhibitory and activating receptors for MHC Class I and Class I-like …

Regulation of natural killer cell activity

SE Kirwan, DN Burshtyn - Current opinion in immunology, 2007 - Elsevier
Information regarding the role of natural killer (NK) cells in the response to viruses,
intracellular bacteria and parasites continues to emerge. NK cells can directly lyse infected …

Specific and non-specific natural killer cell responses to viral infection

WM Yokoyama - Mechanisms of Lymphocyte Activation and Immune …, 2005 - Springer
Initially identified by their ability to kill tumor cells without prior sensitization of the host,
natural killer (NK) cells are now known to provide a crucial initial defense against …

Natural killer cells as an initial defense against pathogens

MB Lodoen, LL Lanier - Current opinion in immunology, 2006 - Elsevier
Natural killer (NK) cells serve as a crucial first line of defense against tumors and a diverse
range of pathogens. Recognition of infection by NK cells is accomplished by the activation of …

Whatever turns you on: accessory-cell-dependent activation of NK cells by pathogens

KC Newman, EM Riley - Nature Reviews Immunology, 2007 - nature.com
Natural killer (NK) cells have a crucial role in combating infections and cancers and their
surface receptors can directly recognize and respond to damaged, transformed or non-self …

Activation and function of natural killer cell responses during viral infections

CA Biron - Current opinion in immunology, 1997 - Elsevier
Although the role of natural killer (NK) cells in defense against certain viral infections has
been appreciated for a number of years, characterization of the virus-induced endogenous …

Immune evasion of natural killer cells by viruses

S Jonjić, M Babić, B Polić, A Krmpotić - Current opinion in immunology, 2008 - Elsevier
Natural killer (NK) cells are important in the host resistance to viral infections. They are
among the first cells to sense the release of proinflammatory cytokines, as well as the …

Natural killer cells in immunodefense against infective agents

N Zucchini, K Crozat, T Baranek… - Expert review of anti …, 2008 - Taylor & Francis
Following the discovery of innate immune receptors, the topics of innate immunity and its
role in defense against infective agents have recently blossomed into very active research …