Neural tube defects (NTDs) are serious malformations affecting approximately 1 per 1000
births, yet the mechanisms by which they arise are unknown. There have been consistent …

BACKGROUND: Neural tube defects (NTDs), including spina bifida and anencephaly, are
the second most common birth defect with an incidence of 1/1000. Genetic factors are …

Neural tube defects (NTD) remain a major cause of morbidity in spite of the reduction in
liveborn incidence with periconceptional folic acid. However, the etiology remains unknown …

The molecular requirements for neural tube closure are complex. This is illustrated by the
occurrence of neural tube defects (NTDs) in many genetic mouse mutants, which implicate a …

Neural tube defects (NTDs) represent a failure of the neural plate to complete the
developmental transition to a neural tube. NTDs are the most common birth anomaly of the …

Neural tube defects (NTDs) are a common birth defect, seen in approximately 1/1,000 births
in the United States. NTDs are considered a complex trait where several genes, interacting …

Neural tube defects (NTD) are one of the most common birth defects and are caused by both
environmental and genetic factors. The approach to identifying the genes predisposing to …

Background Neural Tube Defects (NTDs) are among the most prevalent and most severe
congenital malformations worldwide. Polymorphisms in key genes involving the folate …

Neural tube defects (NTD) arise in the first weeks of pregnancy due to a combination of
environmental and genetic factors. In mothers of children with NTD elevated homocysteine …

Neural tube defects (NTDs) are severe congenital malformations affecting 1 in every 1000
pregnancies.'Open'NTDs result from failure of primary neurulation as seen in anencephaly …