RIPC provides neuroprotection against ischemic stroke by suppressing apoptosis via the mitochondrial pathway

J Lv, W Guan, Q You, L Deng, Y Zhu, K Guo, X Gao… - Scientific Reports, 2020 - nature.com
Ischemic stroke is a common disease with high morbidity and mortality. Remote ischemic
preconditioning (RIPC) can stimulate endogenous protection mechanisms by inducing …

HIF-1α/Beclin1-mediated autophagy is involved in neuroprotection induced by hypoxic preconditioning

N Lu, X Li, R Tan, J An, Z Cai, X Hu, F Wang… - Journal of Molecular …, 2018 - Springer
Hypoxic preconditioning (HPC) exerts a protective effect against hypoxic/ischemic brain
injury, and one mechanism explaining this effect may involve the upregulation of hypoxia …

Voluntary exercise preconditioning activates multiple antiapoptotic mechanisms and improves neurological recovery after experimental traumatic brain injury

Z Zhao, B Sabirzhanov, J Wu, AI Faden… - Journal of …, 2015 - liebertpub.com
Physical activity can attenuate neuronal loss, reduce neuroinflammation, and facilitate
recovery after brain injury. However, little is known about the mechanisms of exercise …

[PDF][PDF] Sirt1 mediates improvement in cognitive defects induced by focal cerebral ischemia following hyperbaric oxygen preconditioning in rats

P Ding, D Ren, S He, M He, G Zhang, Y Chen… - Physiological …, 2017 - biomed.cas.cz
Hyperbaric oxygen preconditioning (HBO-PC) has been proposed as a safe and practical
approach for neuroprotection in ischemic stroke. However, it is not known whether HPO-PC …

[HTML][HTML] Remote ischemic postconditioning confers neuroprotective effects via inhibition of the BID-mediated mitochondrial apoptotic pathway

X Gao, Y Liu, Y Xie, Y Wang… - Molecular medicine …, 2017 - spandidos-publications.com
Ischemic postconditioning has been demonstrated to alleviate brain ischemia/reperfusion-
induced neuronal apoptosis; however, the protective mechanisms underlying the improved …

A Novel Neuroprotective Strategy for Ischemic Stroke: Transient Mild Acidosis Treatment by CO2 Inhalation at Reperfusion

YY Fan, Z Shen, P He, L Jiang, W Hou… - Journal of Cerebral …, 2014 - journals.sagepub.com
Acidosis is one of the key components in cerebral ischemic postconditioning that has
emerged recently as an endogenous strategy for neuroprotection. We set out to test whether …

Ischemic postconditioning alleviates cerebral ischemia–reperfusion injury through activating autophagy during early reperfusion in rats

Y Sun, T Zhang, Y Zhang, J Li, L Jin, Y Sun… - Neurochemical …, 2018 - Springer
This study aimed to investigate whether ischemic postconditioning (IpostC) alleviates
cerebral ischemia/reperfusion (I/R) injury involved in autophagy. Adult Sprague–Dawley rats …

cPKCγ-modulated autophagy in neurons alleviates ischemic injury in brain of mice with ischemic stroke through Akt-mTOR pathway

H Wei, Y Li, S Han, S Liu, N Zhang, L Zhao… - Translational stroke …, 2016 - Springer
We have reported that neuron-specific conventional protein kinase C (cPKC) γ is involved in
the development of cerebral hypoxic preconditioning (HPC) and the neuroprotection against …

Remote limb ischemic postconditioning protects against cerebral ischemia-reperfusion injury by activating AMPK-dependent autophagy

H Guo, L Zhao, B Wang, X Li, H Bai, H Liu, L Yue… - Brain Research …, 2018 - Elsevier
Remote limb ischemic postconditioning (RIPoC) is a promising adjunct treatment for
cerebral ischemia-reperfusion (IR) injury. However, the underlying mechanisms have not …

Remote Ischemic Postconditioning-Mediated Neuroprotection against Stroke by Promoting Ketone Body-Induced Ferroptosis Inhibition

L Huang, Y Zhang, Y Liu, Z Liang, J Chen… - ACS Chemical …, 2024 - ACS Publications
Neuronal death resulting from ischemic stroke is the primary cause of adult mortality and
disability, and effective neuroprotective agents for poststroke intervention are still lacking …